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    Protocol

    Lateral Filter Array Microfluidic Devices for Detecting Circulating Tumor Cells

    Circulating tumor cells (CTCs) are an important liquid biopsy biomarker for next-generation cancer diagnosis and prognosis. However, their clinical usage is hindered by the rarity of CTCs in patient’s peripher...

    Kangfu Chen, Thomas J. George, Z. Hugh Fan in Microfluidic Systems for Cancer Diagnosis (2023)

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    Protocol

    High-Throughput Separation and Enrichment of Rare Malignant Tumor Cells from Large-Volume Effusions by Inertial Microfluidics

    Detection of malignant tumor cells (MTCs) in pleural effusions is essential for determining the malignancy. However, the sensitivity of MTC detection is significantly decreased due to the existence of a massiv...

    Chen Ni, Zhixian Zhu, Zheng Zhou, Nan **ang in Microfluidic Systems for Cancer Diagnosis (2023)

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    Protocol

    Mobile ELISA with a Transparent Incubator

    Enzyme-linked immunosorbent assay (ELISA) is one of the most important technologies for biochemical testing critical for diagnosis and monitoring of many diseases. Traditional systems for ELISA incubation and ...

    Arsenii Zhdanov, Cassidy Chen, Crystal Schmitt in Biomedical Engineering Technologies (2022)

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    Protocol

    Wireless Wearable Ultrasound Sensor to Characterize Respiratory Behavior

    A wireless wearable sensor on a paper substrate was used to continuously monitor respiratory behavior that can extract and deliver clinically relevant respiratory parameters to a smartphone. Intended to be pla...

    Ang Chen, Rachel Diane Rhoades, Andrew Joshua Halton in Biomedical Engineering Technologies (2022)

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    Protocol

    Micromachined Optical Fiber Sensors for Biomedical Applications

    Optical fibers revolutionized the rate of information reception and transmission in telecommunications. The revolution has now extended to the field of physicochemical sensing. Optical fiber sensors (OFSs) hav...

    Chen Zhu, Rex E. Gerald II, Jie Huang in Biomedical Engineering Technologies (2022)

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    Protocol

    Electrochemistry Coupling Localized Surface Plasmon Resonance for Biochemical Detection

    Localized surface plasmon resonance (LSPR) associated with metal nanostructures has developed into highly useful sensor techniques. LSPR spectroscopy often shows absorption peaks which could be used for biomed...

    Zetao Chen, Yanli Lu, Qingqing Zhang, Diming Zhang in Biomedical Engineering Technologies (2022)