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  1. Protocol

    Structural Classification of CDR-H3 in Single-Domain VHH Antibodies

    The immune systems protect vertebrates from foreign molecules or antigens, and antibodies are important mediators of this system. The sequences and structural features of antibodies vary depending on species. ...

    Daisuke Kuroda, Kouhei Tsumoto in Computer-Aided Antibody Design (2023)

  2. Protocol

    Correction to: DIA Proteomics and Machine Learning for the Fast Identification of Bacterial Species in Biological Samples

    The original version of the book was published with an incorrect image for Figure 1 of Chapter 21, which has been corrected by replacing with the correct artwork as given below

    Florence Roux-Dalvai, Mickaël Leclercq, Clarisse Gotti in Proteomics in Systems Biology (2022)

  3. Protocol

    Correction to: Multiscale Modeling of the Mitochondrial Origin of Cardiac Reentrant and Fibrillatory Arrhythmias

    The chapter was inadvertently published with one of the co-author’s surname incorrectly spelled as “Sohljoo” instead of “Solhjoo”

    Soroosh Solhjoo, Seulhee Kim, Gernot Plank in Computational Systems Biology in Medicine … (2022)

  4. Protocol

    Analysis of Small RNA Sequencing Data in Plants

    Over the past decades, next-generation sequencing (NGS) has been employed extensively for investigating the regulatory mechanisms of small RNAs. Several bioinformatics tools are available for aiding biologists...

    Vanika Garg, Rajeev K. Varshney in Plant Bioinformatics (2022)

  5. Protocol

    Virtual Populations for Quantitative Systems Pharmacology Models

    Quantitative systems pharmacology (QSP) places an emphasis on dynamic systems modeling, incorporating considerations from systems biology modeling and pharmacodynamics. The goal of QSP is often to quantitative...

    Yougan Cheng, Ronny Straube, Abed E. Alnaif, Lu Huang, Tarek A. Leil in Systems Medicine (2022)

  6. Protocol

    Scripting Analyses of Genomes in Ensembl Plants

    Ensembl Plants (http://plants.ensembl.org) offers genome-scale information for plants, with four releases per year. As of release 47 (April 2020) it features 79 species ...

    Bruno Contreras-Moreira, Guy Naamati, Marc Rosello, James E. Allen in Plant Bioinformatics (2022)

  7. Protocol

    CyVerse for Reproducible Research: RNA-Seq Analysis

    Posing complex research questions poses complex reproducibility challenges. Datasets may need to be managed over long periods of time. Reliable and secure repositories are needed for data storage. Sharing big ...

    Jason Williams in Plant Bioinformatics (2022)

  8. Protocol

    Correction to: RNA Bioinformatics

    In the original version of this book, chapter 8 was published with incomplete list of authors. This has now been rectified in this revised version of the book.

    Ernesto Picardi in RNA Bioinformatics (2021)

  9. Protocol

    Correction to: Alignment of Biological Sequences with Jalview

    This chapter was mistakenly published non-open access. It has been updated to open access under a CC BY 4.0 license and the Copyright Holder changed to "The Author(s)". The book has also been updated to reflec...

    James B. Procter, G. Mungo Carstairs, Ben Soares in Multiple Sequence Alignment (2021)

  10. Protocol

    Correction to: Cryopreservation of Potato Shoot Tips for Long-Term Storage

    Chapter 2 was previously published non-open access. It has now been changed to open access under a CC BY 4.0 license, and the copyright holder updated to ‘The Author(s)’. The book has been updated with this ch...

    Rainer Vollmer, Janeth Espirilla, Rosalva Villagaray, José Cárdenas in Solanum tuberosum (2021)

  11. Protocol

    Correction to: Proteomics Data Analysis

    In the original version of this book, chapter 16 was published non-open access. It has now been changed to open access under a CC BY 4.0 license, and the copyright holder has been updated to “The Author(s).” T...

    Daniela Cecconi in Proteomics Data Analysis (2021)

  12. Protocol

    Correction to: Development and Optimization of Clinical Informatics Infrastructure to Support Bioinformatics at an Oncology Center

    The book has been inadvertently published with wrong affiliation for the corresponding author, Randa M. Perkins, of chapter 1. It has now been updated as below in this revised version of the book.

    Randa M. Perkins, Joseph Markowitz in Translational Bioinformatics for Therapeut… (2021)

  13. Protocol

    Profiling of RNA Structure at Single-Nucleotide Resolution Using nextPARS

    RNA molecules play important roles in almost every cellular process, and their functions are mediated by their sequence and structure. Determining the secondary structure of RNAs is central to understanding RN...

    Uciel Chorostecki, Jesse R. Willis, Ester Saus, Toni Gabaldon in RNA Bioinformatics (2021)

  14. Protocol

    Deep Learning for Protein–Protein Interaction Site Prediction

    Protein–protein interactions (PPIs) are central to cellular functions. Experimental methods for predicting PPIs are well developed but are time and resource expensive and suffer from high false-positive error ...

    Arian R. Jamasb, Ben Day, Cătălina Cangea, Pietro Liò in Proteomics Data Analysis (2021)

  15. Protocol

    Alignment of Biological Sequences with Jalview

    In this chapter, we introduce core functionality of the Jalview interactive platform for the creation, analysis, and publication of multiple sequence alignments. A workflow is described based on Jalview’s core...

    James B. Procter, G. Mungo Carstairs, Ben Soares in Multiple Sequence Alignment (2021)

  16. Protocol

    Cryopreservation of Potato Shoot Tips for Long-Term Storage

    Cryopreservation is currently the only method which allows long-term conservation of living clonal plant material in the vapor or liquid phase of nitrogen (at −140 to −196 °C) allowing tissue to be viable for ...

    Rainer Vollmer, Janeth Espirilla, Rosalva Villagaray, José Cárdenas in Solanum tuberosum (2021)

  17. Protocol

    RNA-Seq Data Analysis in Galaxy

    A complete RNA-Seq analysis involves the use of several different tools, with substantial software and computational requirements. The Galaxy platform simplifies the execution of such bioinformatics analyses b...

    Bérénice Batut, Marius van den Beek, Maria A. Doyle, Nicola Soranzo in RNA Bioinformatics (2021)

  18. Protocol

    Correction to: Statistical Population Genomics

    Chapter 2, “Processing and Analyzing Multiple Genomes Alignments with MafFilter,” was previously published without including the Electronic Supplementary Material. This has now been included in the revised ver...

    Julien Y. Dutheil in Statistical Population Genomics (2020)

  19. Protocol

    Population Genomics in the Great Apes

    The great apes play an important role as model organisms. They are our closest living relatives, allowing us to identify the genetic basis of phenotypic traits that we think of as characteristically human. How...

    David Castellano, Kasper Munch in Statistical Population Genomics (2020)

  20. Protocol

    Biological Assembly Comparison with VAST+

    The VAST+ algorithm is an efficient, simple, and elegant solution to the problem of comparing the atomic structures of biological assemblies. Given two protein assemblies, it takes as input all the pairwise st...

    Thomas Madej, Aron Marchler-Bauer, Christopher Lanczycki in Structural Bioinformatics (2020)

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