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    Chromatin Immunoprecipitation Assays: Application of ChIP-on-Chip for Defining Dynamic Transcriptional Mechanisms in Bone Cells

    Normal cell growth and differentiation of bone cells requires the sequential expression of cell type specific genes to permit lineage specification and development of cellular phenotypes. Transcriptional activ...

    Margaretha van der Deen, Mohammad Q. Hassan, Jitesh Pratap… in Osteoporosis (2008)

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    In Situ Nuclear Organization of Regulatory Machinery

    Regulatory machinery for gene expression, replication, and repair are architecturally organized in nuclear microenvironments. This compartmentalization provides threshold concentrations of macromolecules for t...

    Shirwin M. Pockwinse, Sayyed K. Zaidi, Ricardo F. Medina, Rachit Bakshi… in Osteoporosis (2008)