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Rechtsprechung zu toxikologischen Schwellenwerten
Toxicological thresholds such as Acceptable Daily Intake, Acute Reference Dose, and Lowest Observed Adverse Effect Level are used to assess food...
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Cystein-Cathepsine: Biochemie trifft Krebsmedizin
Cysteine-Cathepsins are potent lysosomal proteases with many functions in cell physiology. Their dysregulated activity is now a widely accepted...
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Die Rolle von Photorespiration unter dynamischen Lichtbedingungen
Plants use photosynthesis to convert light into metabolic energy. This energy is used to produce carbohydrates and to fuel other metabolic pathways....
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Die Rolle von OPA1 bei der Fusion von Mitochondrien
Mitochondria form extensive networks that rapidly adapt to cellular demands. The formation and disassembly of these structures result from a balance...
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Regulation physiologischer Zellreaktionen durch Rezeptor-Clustering
Cells sense their environment, receive, and process a diverse set of chemical and mechanical signals through transmembrane receptors. How receptors...
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Blick ins Innere: Analyse von 3D-Kulturen mittels Mikrokavitätenarrays
Three-dimensional cultures are a big step towards a more accurate mimicry of the in vivo environment. Given the limited availability of non-invasive...
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Mitochondriale ROS-Produktion bestimmt ACSL4/LPCAT2-gesteuerte Ferroptose
Ferroptosis is a form of iron-dependent regulated cell death, which has been linked to various neurodegenerative diseases. The overexpression of the...
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Nitrogenasen: Vielfältige Katalysatoren für eine nachhaltige Bioökonomie?
Nitrogenases are the only enzymes that reduce molecular nitrogen (N 2 ) to ammonia. Recently, we could demonstrate that nitrogenases also reduce the...
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Bestimmung der Transfektionseffizienz mit dem Mikroplattenreader
Transfection efficiency is e.g. measured to study gene expression, for gene silencing or to produce proteins in large scale. In addition to classic...