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Chapter and Conference Paper
In Vivo Magnetic Resonance of Amyloid Plaques in Alzheimer’s Disease Model Mice
A key feature of Alzheimer’s disease (AD) is the deposition of the amyloid β (Aβ) as neuritic plaques in the brain. Transgenic mice overexpressing mutant amyloid precursor protein (APP), or both mutant APP and...
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Chapter and Conference Paper
Receptor Mediated Toxicity: The Dioxin Receptor as an Example of Biological Complexity and Experimental Approaches
During the past decade tremendous advances have been made in understanding the role of receptors as signal transducers, linking cells and their environment in a carefully orchestrated symphony of multicellular...