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Chapter and Conference Paper
Design of moving-actuator total artificial heart (Korean Heart)
A new version of the moving-actuator electromechanical total artificial heart was designed, to improve total efficiency, durability, and fit inside the thoracic cavity. In contrast to our previous model, with ...
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Chapter and Conference Paper
Implantable Controller with Fault Tolerance for the Moving-Actuator Total Artificial Heart (TAH): Use of a Dual Board
An implantable dual controller with fault tolerance for a total artificial heart (TAH) was developed and evaluated by in vivo studies. The TAH controller has problems normally caused by driving inductive loads...
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Chapter and Conference Paper
Orthotopic Implantation of the Tether-Free Moving-Actuator Type Total Artificial Heart in Sheep
An electromechanical total artificial heart (TAH) was developed. Its fitting trials were performed with computer simulations, and we orthotopically implanted it in 60- to 70-kg sheep in tether-free operations....
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Chapter and Conference Paper
Automatic Control Algorithm for Cardiac Output Regulation of the Total Artificial Heart (TAH)
An automatic control algorithm for the moving-actuator type total artificial heart (TAH) was developed based on motor current waveform analysis. Instead of using relatively complicated analysis of the instanta...
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Chapter and Conference Paper
Further Development of the Moving-Actuator Type Total Artificial Heart
The electromechanical total artificial heart (TAH) developed at Seoul National University Hospital was verified as acceptable for human implantation through several successful animal experiments. In the last t...
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Chapter and Conference Paper
An Adaptive Cardiac Output Control for the Total Artificial Heart Using a Self-Tuning Proportional-Integral-Derivative (PID) Controller
The development of a control method for the totally implantable artificial heart (TAH) to regulate cardiac output according to the change in physiological demand was the goal of this study. The conventional pr...
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Chapter and Conference Paper
Automatic Regulation of Output of an Electrohydraulic Left Ventricular Assist Device Using the Polymer Bellows Water Pressure and Motor Current
An electrohydraulically driven left ventricular assist device (LVAD) has been developed in our laboratory. Over years of in vitro and in vivo testing, a “suction” problem has been pointed out as one of the maj...
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Chapter and Conference Paper
Repetitive Administration of Hemoglobin Raffimer in Experimental Models and Clinical Applications
Hemoglobin (Hb)-raffimer (Hemolink) is an oxygen therapeutic based on human Hb that is intramolecularly and intermolecularly crosslinked with o-raffinose. Hb-raffimer appears to be free of severe toxicity, as ...
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Chapter and Conference Paper
Cranioplasty effect on the cerebral hemodynamics and cardiac function
Background Cranioplasty is usually performed for aesthetic, protective and patient comfort reasons. The objective of this study is to examine the effects of cranioplasty on the cerebral h...
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Chapter and Conference Paper
DNA Microarray Classification Using Single Hidden-Layer Feedforward Networks Trained by SVD
The development of computational algorithms in analyzing microarray data has attracted many researchers in recent years. Especially statistical and machine learning approaches can provide powerful tools for bi...
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Chapter and Conference Paper
Long-Term Outcome of Gamma Knife Surgery Using a Retrogasserian Petrous Bone Target for Classic Trigeminal Neuralgia
Background: Gamma knife surgery (GKS) is the prevailing method for treatment of medically intractable trigeminal neuralgia (TN), although there are some technical differences among radiosurgical ce...