11 Result(s)
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Chapter and Conference Paper
Peritumoral Brain Edema and Cortical Damage by Meningioma
Forty supratentorial meningiomas were analyzed to identify factors causing peritumoral brain edema. Parasagittal, sphenoid ridge, and olfactory groove meningiomas induced edema more frequently than those in ot...
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Chapter and Conference Paper
Microcirculatory Disturbance and Leukocytes: Influence of Leukocyte-Produced Superoxide on Red Blood Cell Aggregation
It is well recognized that cerebral circulation is regulated by perfusion pressure together with cerebrovascular resistance. Cerebrovascular resistance is dependent upon intracranial pressure, organic changes ...
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Chapter and Conference Paper
The Effect of BAY K-8644 on Cytotoxic Edema Induced by Total Ischemia of Rat Brain
The calcium channel activator BAY K-8644, a dihydropyridine (DHP) derivative, has been shown to possess neurochemical and behavioral activities, but its effect on ischemic brain damage has remained unknown. Th...
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Chapter and Conference Paper
Morphological Changes of Cultured Neuronal and Endothelial Cells by Human Albumin
The role of plasma proteins in the mechanisms of brain tissue damage in ischemic events remains to be clarified. The purpose of this study was to investigate whether the presence of albumin in the extracellula...
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Chapter and Conference Paper
An Assessment of Progression of Brain Edema with Amino Acid Levels in Cerebrospinal Fluid and Changes in Electroencephalogram in an Adult Cat Model of Cold Brain Injury
We investigated the relationship between the changes of the electroencephalogram (EEG) and concentration of amino acids (AAs) in cerebrospinal fluid (CSF) using a model of cold brain injury. A cold injury was ...
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Chapter and Conference Paper
Effect of YM737, a New Glutathione Analogue, on Ischemic Brain Edema
We investigated the effect of YM737, a monoester of glutathione (GSH), on brain edema and GSH content after occlusion of a middle cerebral artery (MCA) in the rat. The drug possesses stronger radical scavengin...
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Chapter and Conference Paper
CSF α1-Antichymotrypsin and Antitrypsin in Multi-Infarct Dementia and Alzheimer’s Disease
Alzheimer’s disease (DAT) is a degenerative disorder of the central nervous system that results in a progressive loss of memory and other intellectual functions beginning in middle to late life. Certain neurop...
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Chapter and Conference Paper
Immunohistochemical and In Situ Hybridization. Evidence for a Calcium-Binding Protein in the Sinus Nerve
There is evidence for the presence of a class of soluble proteins that bind intracellular calcium ions and may be involved in controlling intracellular calcium ion concentrations (1). Among various calcium-bin...
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Chapter and Conference Paper
Effect of Glutamate and Its Antagonist on Shift of Water from Extra- to Intracellular Space After Cerebral Ischaemia
The effects of glutamate and the excitatory amino acid antagonist, MK-801, were investigated on the time course of the shift of water from extracellular to intracellular space (progression or cytotoxic oedema)...
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Chapter and Conference Paper
Calcium Antagonists and a Rapid Shift of Water from Extracellular to Intracellular Space After Cerebral Ischemia
In many respects calcium plays a key role in the central nervous system. Calcium antagonists may serve as protective agents in cerebral hypoxia or ischemia and may be useful in the treatment of cerebrovascular...
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Chapter and Conference Paper
Some Rheological Considerations in Ischemic Cerebrovascular Disease — Blood Viscosity, RBC Aggregation, and RBC Zeta Potential
It is well known that blood viscosity is one of the most important determinants of cerebral blood flow (CBF) in normal and diseased states. It is also well recognized that blood viscosity is mainly influenced ...
