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Chapter and Conference Paper
A Rare Case of a Large Spinal Meningioma with Mediastinal Extension and Malignant Behavior Classified Histologically as Benign
Aim: To report a rare case of a spinal WHO grade I meningioma extending through intervertebral foramina C7 to D4 with an extensive mediastinal mass and infiltration of the vertebrae, and to discuss the malignant ...
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Chapter and Conference Paper
The Use of Sandostatin® in Insulinomas. The Relation Between In Vivo Responses, the Presence of Somatostatin Receptors and the Development of Tachyphylaxis
Patients with insulin-secreting islet cell tumors are at risk for severe, protracted hypoglycemia. Surgical removal of the tumor is the treatment of choice. During the diagnostic work up, medical treatment for...
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Chapter and Conference Paper
Chemical Structure, Pharmacodynamic Profile and Pharmacokinetics of SMS 201–995 (Sandostatin®)
Natural somatostatin (SRIF) is a tetra-decapeptide with a multiplicity of inhibiting actions on the secretion of a variety of hormones. In vivo, the compound has a biological half-life of only two to three minute...