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Mechanical and Microwave Resonators for Sensing and Sizing Single Cells
Repeated size measurements on a single cell can provide critical information about its physiological state. The growth and decay rates of cellular...
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Integrated Microwell Array Technologies for Single Cell Analysis
Microwell arrays are an important tool for high-throughput single cell analysis, with different approaches of microwell-based studies being described...
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Liposome-Mediated Material Transfer in Single Cells
Liposomes are artificially prepared lipid bilayer vesicles. Among these, unilamellar liposomes are reminiscent of intracellular and extracellular...
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Single-Cell Technologies for Cancer Therapy
Routine sequencing techniques used in cancer diagnosis have primarily focused on bulk tissue genomic analysis. However, cell heterogeneity is a...
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Acoustic Tweezers for Single-Cell Manipulation
Acoustic tweezers are dexterous tools to manipulate or probe single cells with high precision. Compared to magnetic-, optical-, optoelectronic-,...
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Dual-Well Microfluidic Technique for Single Cell Isolation and Long-Term Clonal Culture
The clonal culture of single cells is widely used for studying cell dynamics and heterogeneity in vitro and producing monoclonal cell populations....
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Record the Single Cell Signal Pathway
Systems biology promises to deliver a holistic time and space understanding of biological processes with applications including the identification of...
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Single-Cell Transcriptome Sequencing Using Microfluidics
Cellular heterogeneity is a hallmark of multicellular life, providing organisms various forms and functions by facilitating specialization. With such...
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Biochemical Analysis of Secreted Molecules by Individual Cells
Secreted proteins and metabolites are key components of functional homeostasis and organize individual cells into tissues and organisms. Various...
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Transmembrane Receptor Dynamics as Biophysical Markers for Assessing Cancer Cells
As biophysical properties of tissues and cells play essential roles in cellular function, morphogenesis, and disease progression, numerous...
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Cytometry of Single Cell in Biology and Medicine
It has been a very long time for human to understand the physiological processes related to health, disease, and death. Cell is the basic elementary...
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Microinjection for Single-Cell Analysis and Therapy
Microinjection is a century-old technique which is being utilized in a wide variety of single-cell analysis as well as for intracytoplasmic sperm...
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Single Cell Adhesion in Cancer Progression
Quantitative assessment of cell adhesion during pathological development can potentially lead to a better elucidation of the mechanisms behind...
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Analytical Technology for Single-Cancer-Cell Analysis
Traditional analysis in cancer initiates an empirical screening on bulk tumors based on standard equipment. Nonetheless, the tumors inherently...
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Single-Cell Microencapsulation for Evolution and Discovery of Biocatalysts
Enzymes are responsible for many chemical reactions which support life and are used in numerous industries. Laboratory evolution experiments can...
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Technologies for Automated Single Cell Isolation
The isolation of individual cells has gained tremendous importance with the advent of new methods for highly parallel single-cell analysis. A...
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Microfluidic and Nanomaterial Approach for Virology
Viral infectious diseases can erupt rapidly and are capable of causing massive health issues. Recent evidence on their high specificity over host...
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Digital Microfluidics for Single Cell Manipulation and Analysis
An investigation of cells at the level of a single cell has been recently possible and widely adopted in clinical and biological studies....
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Light-Induced Cellular Delivery and Analysis
In the era of advanced nanotechnology, laser-assisted photoporation is of particular importance for the delivery of membrane impermeable biomolecules...
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Single-Cell Impedance Flow Cytometry
This chapter reviews recent technical developments in the field of single-cell electrical property characterization. Firstly, three well-established...