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Chapter and Conference Paper
Expression of High Affinity IL-2 Receptors on a Hodgkin Cell Line
Recent data based on genetic analysis of immunoglobulin and T cell receptor gene rearrangements suggest that Hodgkin (H) and Sternberg-Reed (SR) cells have characteristics of lymphoid cells [3, 5, 19]. It has ...
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Chapter and Conference Paper
Biology of Hodgkin Cell Lines
Studies to characterize Hodgkin and Reed-Sternberg cells in histological sections have yielded many conflicting data over the years. Even with progress in immunohistological technology, the histogenetic deriva...
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Chapter and Conference Paper
Diagnostic Strategies and Staging Procedures for Hodgkin’s Lymphoma: Bone Marrow Scintigraphy and Magnetic Resonance Imaging
In Hodgkin's lymphoma the bone marrow is infrequently involved. Clinical diagnosis is usually made by bone marrow biopsy. Because biopsy is blind, false-negative results often occur. For imaging of the bone ma...
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Chapter and Conference Paper
Conventional Salvage Therapy for Hodgkin’s Lymphoma
High remission rates are obtained in advanced Hodgkin’s lymphoma utilizing combination chemotherapy such as MOPP (mustargen, vincristine, procarbazine, and prednisone) (DeVita et al. 1970; Longo et al. 1986) a...
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Chapter and Conference Paper
Bone Marrow Transplantation in the Treatment of Hodgkin’s Lymphoma: Problems, Remaining Challenges, and Future Prospects
Table 1 summarizes the results of autologous bone marrow transplantation (ABMT) in more than 200 patients. The results seem to be rather consistent between the groups who have the largest published series of A...
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Chapter and Conference Paper
Radiolabeled Monoclonal Antibodies Against Reed-Sternberg Cells for in Vivo Imaging of Hodgkin’s Disease by Immunoscintigraphy
Although it is characterized by its propensity for dissemination, Hodgkin’s disease (HD) can be cured by locoregional irradiation (Carde et al. 1988; Kaplan 1980; Tubiana et al. 1985). Since intensive chemothe...
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Chapter and Conference Paper
Risk Factor Adapted Treatment of Hodgkin’s Lymphoma: Strategies and Perspectives
Although modern therapy strategies have considerably improved the prognosis of Hodgkin’s lymphoma, in general the results for stages I, II, and IIIA with mediastinal tumor, spleen, or extranodal involvement an...