Page
%P
![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
-
Chapter
Site-Directed Mutagenesis of Residues in the Active Site of Sepiapterin Reductase
Tetrahydrobiopterin (BH4) is the natural cofactor for producing neurotransmitters such as catecholamines, indoleamines, and nitric oxide. Sepiapterin reductase (SPR; EC 1. 1. 1. 153) catalyzes the terminal step i...