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    Chapter

    Deacceleration of Brain Aging by Melatonin

    Melatonin counteracts several pathophysiological processes that promote brain aging. A central feature of these aging-accelerating changes is low-grade brain inflammation, which may progressively aggravate, es...

    Rüdiger Hardeland in Inflammation, Aging, and Oxidative Stress (2016)

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    Chapter

    An Ancient Cellular Mechanism in the Tension Field between Energy Requirements and Destruction Avoidance

    Circadian rhythmicity is a fundamental biological phenomenon of almost ubiquitous importance. This kind of an endogenous, innate oscillation with a period length of about a day is present in the majority of or...

    Rüdiger Hardeland in The Redox State and Circadian Rhythms (2000)

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    Chapter

    Circadian Rhythms and Oxidative Stress in Non-vertebrate Organisms

    Several lines of evidence suggest that the circadian organization of living beings is important for avoiding excessive oxidative stress under physiological conditions. In the dinoflagellate Gonyaulax polyedra, ac...

    Rüdiger Hardeland, Ana Coto-Montes… in The Redox State and Circadian Rhythms (2000)