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    Chapter

    Discovery of Green Tea Polyphenol-Based Antitumor Drugs: Mechanisms of Action and Clinical Implications

    Green tea polyphenols, especially catechins, have shown great promise for use as anticancer agents. One such catechin, epigallocatechin-3 gallate (EGCG), is of particular interest due to mounting evidence of i...

    Reda Saber Ibrahim Ahmed, Claire Soave, Tracey Guerin Edbauer in Medicinal Plants (2019)

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    Chapter

    Proteasome Inhibitors and Lessons Learned from Their Mechanisms of Action and Resistance in Human Cancer

    Selective protein degradation by the ubiquitin–proteasome pathway (UPP) is critical to cellular homeostasis, and dysregulation of the UPP has been associated with human diseases including cancer. Proteasome in...

    Sara M. Schmitt, Rahul R. Deshmukh in Resistance to Proteasome Inhibitors in Can… (2014)

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    Chapter

    Proteasome Inhibition as a Novel Strategy for Cancer Treatment

    The proteasome is a multi-subunit protease complex, responsible for the degradation of misfolded, damaged, or short-lived proteins. Indeed, more than 90 % of intracellular proteins are degraded through the ubi...

    Min Shen, Q. ** Dou in Cell Death Signaling in Cancer Biology and Treatment (2013)

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    Chapter

    Nutritional Compounds as Chemopreventive Agents by Proteasome Inhibition

    Nutritional phytochemicals, distributed throughout the plant kingdom, possess anticancer activities associated with their consumption. This chapter will focus on the cellular activities of phytochemicals, thei...

    Kristin Landis-Piwowar, Elizabeth Smerczak, Jian Zuo in Nutrition, Diet and Cancer (2012)

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    Chapter and Conference Paper

    Abrasion-Resistant Technology and its Prospect for CFB Boilers

    In recent years, CFB boilers (CFBB) have been widely used in the commercial power plants due to its environmental benefits, high combustion efficiency, wide coal flexibility, and some other advantages. At the ...

    H. Zheng, Y. J. Li, L. J. Wang, S. H. Liu in Proceedings of the 20th International Conf… (2010)