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Chapter
Discovery of Green Tea Polyphenol-Based Antitumor Drugs: Mechanisms of Action and Clinical Implications
Green tea polyphenols, especially catechins, have shown great promise for use as anticancer agents. One such catechin, epigallocatechin-3 gallate (EGCG), is of particular interest due to mounting evidence of i...
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Chapter
Proteasome Inhibitors and Lessons Learned from Their Mechanisms of Action and Resistance in Human Cancer
Selective protein degradation by the ubiquitin–proteasome pathway (UPP) is critical to cellular homeostasis, and dysregulation of the UPP has been associated with human diseases including cancer. Proteasome in...
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Chapter
Proteasome Inhibition as a Novel Strategy for Cancer Treatment
The proteasome is a multi-subunit protease complex, responsible for the degradation of misfolded, damaged, or short-lived proteins. Indeed, more than 90 % of intracellular proteins are degraded through the ubi...
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Chapter
Nutritional Compounds as Chemopreventive Agents by Proteasome Inhibition
Nutritional phytochemicals, distributed throughout the plant kingdom, possess anticancer activities associated with their consumption. This chapter will focus on the cellular activities of phytochemicals, thei...
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Chapter and Conference Paper
Abrasion-Resistant Technology and its Prospect for CFB Boilers
In recent years, CFB boilers (CFBB) have been widely used in the commercial power plants due to its environmental benefits, high combustion efficiency, wide coal flexibility, and some other advantages. At the ...