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Repurposing Drugs for Viruses and Cancer: A Novel Drug Repositioning Strategy for COVID-19
The high infection capacity and rapid mutations in coronavirus disease 2019 (COVID-19) has been no stranger to many. The etiological agent that contributed to this global health crisis is by no means the sever...
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Computationally Repurposed Natural Products Targeting SARS-CoV-2 Attachment and Entry Mechanisms
The search for effective and safe therapeutics and vaccines for COVID-19 is one of, if not the top most, the top priorities in today’s medicinal and pharmaceutical research. In COVID-19 drug discovery and deve...
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Engaging with People and Populations in Health Promotion Research: A Snapshot on Participatory Processes
Research on the practices of individuals and populations implies specific methods, approaches and aims. As it seeks to understand the different determinants of these practices and focuses on individuals (or gr...
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Diet Quality and Cerebral Infarction: South Korean Aspects
Cerebral infarction (CI)is caused by an obstruction and/or a fatty deposit lining the walls within a blood vessel that supplies blood to the brain. When either of these events occurs, the likely outcome is bra...
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Radiological Evaluation
Complete resection of a gastric tumor and adjacent lymph nodes is considered the only proven, effective curative treatment [1, 2]. However, the treatment of gastric cancer has become increasingly sophisticated...
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Indications of Laparoscopic Gastrectomy for Gastric Cancer
Kitano et al. [1] reported the first laparoscopy-assisted gastrectomy (LAG) in 1994, and the first laparoscopy-assisted total gastrectomy with a D2 lymphadenectomy for gastric adenocarcinoma was done in 1999 [...
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Photoprotection
Author contributions: Dr. Lim and Dr. Hexsel have participated in the conception and design, drafting and critical revision of the chapter for important intellectual content.
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Complications of Bariatric Surgery
Surgical weight loss procedures are among the most commonly performed operations in the world today. Because it is so prevalent, most general surgeons will likely have to manage bariatric patients acutely even...
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HIV/AIDS and Complications
In the setting of human immunodeficiency virus (HIV) and acquired immune deficiency syndrome (AIDS), two well-characterized syndromes can present with fevers, rash, headache, and other nonspecific complaints t...
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Optimization Models and Computational Approaches for Three-dimensional Conformal Radiation Treatment Planning
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Optimization Tools for Radiation Treatment Planning in Matlab
This chapter describes a suite of optimization tools for radiation treatment planning within the Matlab programming environment. The data included with these tools was computed for real patient cases using a M...
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T cell reactivity to Epstein-Barr virus in rheumatoid arthritis
The notion that T cells could play a central role in rheumatoid arthritis (RA) emerged in the late 70’s with the demonstration of massive T cell infiltration in inflamed joints from RA patients [1]. Support for t...