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Performance Evaluation of Normalization Approaches for Metagenomic Compositional Data on Differential Abundance Analysis

Background: In recent years, metagenomics, as a combination of research techniques without the process of cultivation, has become more and more popular in studying the genomic/genetic variation of microbes in en...

Ruofei Du, Lingling An, Zhide Fang in New Frontiers of Biostatistics and Bioinformatics (2018)