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    Chapter

    VEGF-Mediated Effects on Brain Microvascular Endothelial Tight Junctions and Transmigration of Breast Cancer Cells Across the Blood-Brain Barrier

    Breast cancer spreads to the bones, lungs, brain and liver. While the mechanisms of breast metastasis to bones and lungs have been studied and characterized, there is little information about the molecular bas...

    Shalom Avraham, Shuxian Jiang, Lili Wang, Yigong Fu… in Tight Junctions in Cancer Metastasis (2013)

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    Chapter

    Cellular and Molecular Mechanisms Involved in Breaching of the Blood–Brian Barrier by Circulating Breast Cancer Cells

    Brain metastases are prevalent in lung, melanoma and breast cancers and are associated with high morbidity and mortality. Therefore, targeted treatments and preventative strategies of brain metastasis are need...

    Hava Karsenty Avraham, Shuxian Jiang… in Breast Cancer Metastasis and Drug Resistan… (2013)