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HTLV-I Tax and cell cycle progression
Human T-cell leukemia virus type I (HTLV-I) is the etiological agent for adult T-cell leukemia (ATL) and various human myopathies/neuropathies. HTLV-I encodes a 40 kDa phosphoprotein, Tax, which has been impli...
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HIV-1 Tat: A Transcriptional Activator that Recognizes a Structured RNA Target
The human and simian immunodeficiency viruses (HIVs and SIVs) are unique among retroviruses in encoding for many small regulatory proteins in addition to Gag, Pol and Env (reviewed in 1). Although counterpart ...