4 Result(s)
within
Chapter
Esteban Ballestar
Biomedicine
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Chapter
Disruption of Epigenetic Mechanisms in Autoimmune Syndromes
Autoimmune disorders are a heterogeneous group of both systemic and organ-specific diseases characterized by the abnormal recognition of self-components by the immune system. These are genetically complex dise...
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Chapter
An Introduction to Epigenetics
Eukaryotic genomic information is modulated by a variety of epigenetic modifications that play both a direct role in establishing transcription profiles, modulation of DNA replication and repair processes and ...
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Chapter
Examining DNA–Protein Interactions with Genome-Wide Chromatin Immunoprecipitation Analysis
Understanding the mechanisms by which genomic information is hierarchically organized and used by different cell and tissue types under different physiological conditions requires the detailed analysis of the ...
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Chapter
A Changing Epigenome in Health and Disease
In mammals, epigenetic modifications play an essential role both in establishing transcription profiles and in organizing DNA architecture within the cell nucleus. Specifically, the role of epigenetic modifica...
