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    Chapter and Conference Paper

    A High-Fidelity 3D Micromechanical Model of Ventricular Myocardium

    Pulmonary arterial hypertension (PAH) imposes a pressure overload on the right ventricle (RV), leading to myofiber hypertrophy and remodeling of the extracellular collagen fiber network. While the macroscopic ...

    David S. Li, Emilio A. Mendiola in Functional Imaging and Modeling of the Hea… (2021)

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    Chapter and Conference Paper

    A Micro-anatomical Model of the Infarcted Left Ventricle Border Zone to Study the Influence of Collagen Undulation

    Myocardial infarction (MI) results in cardiac myocyte death and often initiates the formation of a fibrotic scar in the myocardium surrounded by a border zone. Myocyte loss and collagen-rich scar tissue heavil...

    Emilio A. Mendiola, Eric Wang in Functional Imaging and Modeling of the Hea… (2023)

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    Chapter and Conference Paper

    On the Possibility of Estimating Myocardial Fiber Architecture from Cardiac Strains

    The myocardium is composed of a complex network of contractile myofibers that are organized in such a way as to produce efficient contraction and relaxation of the heart. The myofiber architecture in the myoca...

    Muhammad Usman, Emilio A. Mendiola in Functional Imaging and Modeling of the Hea… (2023)