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    Chapter

    Targeting Oncogenic BRAF in Human Cancer

    Mitogen Activated Protein Kinase (MAPK) pathway activation is a frequent event in human cancer and is often the result of activating mutations in the BRAF and RAS oncogenes. BRAF missense mutations, the vast m...

    Christine A. Pratilas, Feng **ng, David B. Solit in Therapeutic Kinase Inhibitors (2012)