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Acute and Chronic Wound Management: Assessment, Therapy and Monitoring Strategies
The dynamic nature of the wound healing is a well-studied process. With the rapid evolution of healthcare science, efforts are being made to design newer therapies, along with advancement in the available tech...
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Hydrogel-Based Tissue-Mimics for Vascular Regeneration and Tumor Angiogenesis
The vital role of structurally and functionally stable vasculature in engineered tissues is well-established in regenerative medicine. Large-volume, natural, and synthetic tissue constructs require a high degr...
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Regenerative Approaches in the Nervous System
The nervous system is the most unique system of the human body in more than one way. The excitable tissue that forms the nervous system generates and transmits electrical impulses that are responsible for comm...
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Understanding LncRNAs in Biomaterials Development for Osteointegration
Osseointegration of implants is a sophisticated healing process comprising of blood clot formation, immune response, angiogenesis, and osteogenesis. The features of the blood clots take a crucial role in fulfi...
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In-Vitro and In-Vivo Tracking of Cell-Biomaterial Interaction to Monitor the Process of Bone Regeneration
Extensive effort in the development of implants or scaffolds with an objective of bone tissue engineering followed the trend in blending suitable chemical and biological properties. Till date, the application ...
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Chapter
Regeneration and Tissue Microenvironment
The human body is composed of trillions of cells, which, despite sharing the same genetic material, differentiate into different cell types. For a long time, scientists have been fascinated by the enigma of ce...
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Immunological Perspectives Involved in Tissue Engineering
Tissue engineering provides the opportunity to construct biomaterial scaffolds to replace or regenerate damaged or injured tissue or organ. However, the implantation-mediated injury, and the biomaterial itself...
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Role of Biosensors in Regenerative Therapeutics: Past, Present, and Future Prospects
Regenerative medicine is an integrative strategy that involves technology and basic sciences to stimulate regeneration in damaged and wounded tissues and organs. A variety of regenerative medicine therapies, s...
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Stem Cells and Therapies in Cardiac Regeneration
Ischemic heart diseases (IHD) are a significant cause of death all over the world increasing the cardiovascular disease (CVD) burden. Blockade of coronary arteries followed by an infarct in the heart is the ba...
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Advances in 3D Printing Technology for Tissue Engineering
Additive manufacturing has emerged as an advanced technology for the precise 3D construction of complex tissue engineering products. Different platforms such as laser-assisted printing, extrusion printing, and...
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Chapter
Adult Neurogenesis: A Potential Target for Regenerative Medicine
The concept of adult neurogenesis has always been a topic that attracted widespread attention from the neuroscience field. Newly formed neurons in localized regions of nervous system under specific internal an...
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Prenatal Interventions for the Treatment of Congenital Disorders
Congenital genetic defects are the leading cause of morbidity and mortality. With progress in diagnostic methods, many of these diseases can be diagnosed prenatally. Prenatal therapeutic interventions can help...
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Current Approaches in Vertical Bone Augmentation and Large Bone Deficiencies in the Orofacial Region
Bone regeneration in the orofacial region is a significant health and economic burden. While surgical techniques for the treatment of bone deficiencies have been developed, several challenges still remain. Thi...
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The Prospects of RNAs and Common Significant Pathways in Cancer Therapy and Regenerative Medicine
Cells undergoing initiation of carcinogenesis and regeneration often share most of the molecular pathways. Consequently, cancer treatment may compromise regenerative processes and vice versa may modulate the i...
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Chapter
Non-stem Cell Mediated Tissue Regeneration and Repair
Regrowth and replacement are two basic responses of the body to any injury. While regrowth is generally attributed to stem cells, and replacement or scarring to non-stem cells, there is much more to the repair...
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Advances in Medical Imaging for Wound Repair and Regenerative Medicine
Adult mammalian wounds commonly heal through the process of repair and leave a permanent mark—the scar. Scars typically jeopardize normal organ function and restrict full function restoration—a process called ...