4 Result(s)
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Chapter
Multiple Bio-imaging Modalities in Evaluation of Epimedium-Derived Phytoestrogenic Fraction for Prevention of Postmenopausal Osteoporosis
Recently, we extracted phytoestrogenic fraction (PF) from herbal Epimedium, which is a kind of traditional Chinese medicine (TCM) known as a “bone-strengthening Chinese herb.” This herb has been widely prescri...
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Chapter
Contrast-Enhanced MRI and Micro-CT Adopted for Evaluation of a Lipid-Lowering and Anticoagulant Herbal Epimedium-Derived Phytoestrogenic Extract for Prevention of Steroid-Associated Osteonecrosis
We developed an alternative steroid-associated osteonecrosis (ON) rabbit model using a combination of a single injection of low-dose lipopolysaccharide (LPS) and three subsequent injections of pulsed high-dose...
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Chapter
Gene therapy for management of lupus: Correction of Fas and Fas ligand-induced apoptosis in murine disease — therapeutic rationale and strategies
Identification of mutations of fas and fas ligand (fasL) in murine models of autoimmune disease have provided an important experimental tools for the analysis of tolerance and autoimmune disease. Mutations of fas...
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Chapter
Apoptosis
Apoptosis is a physiologic process that mediates the death of selected cells. In contrast to necrosis, which results from a strong nonspecific or toxic cell injury, apoptosis is initiated by ligand—receptor in...
