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  1. No Access

    Chapter and Conference Paper

    The Evolution of B-Cell Clones

    Large numbers of B cells are produced throughout life as the result of both primary B lymphopoiesis (Opstelten and Osmond 1983) and antigen-driven B- cell proliferation (Fliedner et al. 1964). It is a feature of ...

    I. C. M. MacLennan, Y. J. Liu, S. Oldfield, J. Zhang, P. J. L. Lane in Immunological Memory (1990)

  2. No Access

    Chapter and Conference Paper

    Wachstumsfaktoren und Zytokine in der inneren Medizin

    Die anerkannteste und am besten untersuchte Hypothese der Pathogenese kardiovaskulärer Erkrankungen ist die „Response to injury hypothesis“ von Ross et al. [5, 11, 15]. Die Hypothese geht davon aus, daß am Beg...

    A. Habenicht, A. J. R. Habenicht… in Verhandlungen der Deutschen Gesellschaft f… (1991)

  3. No Access

    Chapter and Conference Paper

    Wirkungsmechanismus von Valproinsäure: Neurophysiologische Aspekte

    VPA besitzt in den von uns untersuchten In-vitro-Epilepsiemodellen von allen klinisch verwendeten Antikonvulsiva das relativ weiteste Wirk-spektrum. VPA beeinflußt die Erregungsbildung an Nervenzellen sowohl ü...

    U. Heinemann, J. Dreier, J. Stabel, C. L. Zhang, A. Leschinger, E. Ficker in Valproinsäure (1992)

  4. No Access

    Chapter and Conference Paper

    Endothelzellstimulation durch AGE — Ein In-vitro-Modell diabetischer Spätschäden

    Nichtenzymatische Glykosilierung führt zur Bildung von AGE-Proteinen. AGE-Proteine werden über spezifische Rezeptoren, die am Endothel und Makrophagen vorkommen, gebunden, internalisiert und degradiert. AGE-Pr...

    P. P. Nawroth, J. Lu, M. Abel, Y. Zhang, J. Riedesel F.z.E.… in Diabetes und Angiopathie (1993)

  5. No Access

    Chapter and Conference Paper

    Delayed Gene Expression and Ischemic Brain Injury

    There is increasing evidence that cerebral ischemic injury occurs at a slower pace than previously believed. Although in areas of severe ischemia tissue damage occurs relatively rapidly, in regions of less-sev...

    C. Iadecola, M. E. Ross, F. Zhang, S. Nogawa… in Maturation Phenomenon in Cerebral Ischemia… (1999)

  6. No Access

    Chapter and Conference Paper

    Protein Expression and Brain Plasticity After Transient Middle Cerebral Artery Occlusion in the Rat

    After a stroke, both animals and humans can regain lost function. The molecular basis of this functional plasticity is unknown. In this manuscript, we describe developmental protein expression in the ischemic ...

    M. Chopp, Y. Li, Z. G. Zhang in Maturation Phenomenon in Cerebral Ischemia III (1999)

  7. No Access

    Chapter and Conference Paper

    C-Jun is a JNK-Independent Coactivator of the PU.1 Transcription Factor

    The ETS domain transcription factor PU.1 is necessary for the development of monocytes and regulates, in particular, the expression of the monocyte-specific macrophage colony-stimulating factor (M-CSF) recepto...

    G. Behre, A. J. Whitmarsh, M. P. Coghlan, T. Hoang, C. L. Carpenter… in Acute Leukemias VIII (2001)

  8. No Access

    Chapter and Conference Paper

    Thrombosis After Ischemic Stroke-Platelet Aggregation

    After ischemic stroke secondary thrombosis contributes to the expansion of the lesion. This manuscript describes the underlying mechanisms responsible for cerebral thrombosis after stroke. We hypothesize that ...

    M. Chopp, Z. G. Zhang in Maturation Phenomenon in Cerebral Ischemia IV (2001)

  9. No Access

    Chapter and Conference Paper

    Visual Search in Alzheimer’s Disease — fMRI Study

    The aim was to investigate the neural basis of visual attention deficits in Alzheimer’s disease (AD) patients using functional MRI. Thirteen AD patients and 13 age-matched controls participated in the experime...

    **g Hao, Kun-cheng Li, Ke Li, De-xuan Zhang… in Medical Imaging and Augmented Reality (2004)

  10. No Access

    Chapter and Conference Paper

    Shape and Pixel-Property Based Automatic Affine Registration Between Ultrasound Images of Different Fetal Head

    The difficulties in the automatic registration of the ultrasound images of different fetal heads are mainly caused by the poor image quality, view dependent imaging property and the difference of brain tissues...

    Feng Cen, Yifeng Jiang, Zhijun Zhang, H. T. Tsui in Medical Imaging and Augmented Reality (2004)

  11. No Access

    Chapter and Conference Paper

    Efficient Lossy to Lossless Medical Image Compression Using Integer Wavelet Transform and Multiple Subband Decomposition

    Since medical imaging produce prohibitive amounts of data, efficient and low-complexity compression is necessary for storage and communication purposes. In this paper, a flexible coding algorithm called embedd...

    Li-bao Zhang, Ke Wang in Medical Imaging and Augmented Reality (2004)

  12. No Access

    Chapter and Conference Paper

    Assessing Spline-Based Multi-resolution 2D-3D Image Registration for Practical Use in Surgical Guidance

    A spline-based multi-resolution 2D-3D image registration algorithm has recently been introduced [1-3]. However, its accuracy, robustness, and efficiency have not been fully investigated. In this paper, we focu...

    Guoyan Zheng, Xuan Zhang, Lutz-Peter Nolte in Medical Imaging and Augmented Reality (2004)

  13. Chapter and Conference Paper

    Cervical Cancer Detection Using SVM Based Feature Screening

    We present a novel feature screening algorithm by deriving relevance measures from the decision boundary of Support Vector Machines. It alleviates the “independence” assumption of traditional screening methods...

    Jiayong Zhang, Yanxi Liu in Medical Image Computing and Computer-Assis… (2004)

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  14. Chapter and Conference Paper

    A Model for Some Subcortical DTI Planar and Linear Anisotropy

    Linear anisotropy, planar anisotropy and isotropy [1] are used as metrics for different kinds of diffusion in diffusion imaging. While linear anisotropy is reported to correlate to coherent neural fiber struct...

    Song Zhang, David Laidlaw in Medical Image Computing and Computer-Assis… (2004)

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  15. Chapter and Conference Paper

    Color Rapid Prototy** for Diffusion-Tensor MRI Visualization

    We describe work toward creating color rapid prototy** (RP) plaster models as visualization tools to support scientific research in diffusion-tensor (DT) MRI analysis. We currently give surgeons and neurolog...

    Daniel Acevedo, Song Zhang, David H. Laidlaw… in Medical Image Computing and Computer-Assis… (2004)

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  16. No Access

    Chapter and Conference Paper

    Traditionelle chinesische Medizin in der Prävention kardiovaskulärer Erkrankungen — Grundprinzipien, Anwendungshäufigkeit und Wirksamkeit der chinesischen Kräutermedizin

    Traditionelle chinesische Medizin (TCM) wird in ihrem Herkunft sland China bereits seit Jahrtausenden erfolgreich angewandt und heute zusammen mit konventioneller Medizin im Rahmen einer integrierten Behandlun...

    Dr. Martin Thoenes, Zhengguang Zhang… in Prävention und Versorgungsforschung (2008)