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Identification of consensus homozygous regions and their associations with growth and feed efficiency traits in American mink
The recent chromosome-based genome assembly and the newly developed 70K single nucleotide polymorphism (SNP) array for American mink ( Neogale vison )...
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Metagenomic Next-Generation Sequencing as an Effective Diagnostic Tool for Talaromycosis in HIV-Negative Patients
The diagnosis of Talaromyces marneffei infection in HIV-negative patients remains challenging. There is an urgent need for rapid and convenient...
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Foodborne Helminthiasis
Purpose of ReviewThis review focuses on key foodborne helminths: providing an overview of their lifecycles and major transmission routes to humans,...
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Antibacterial activity and biosynthetic potential of Streptomyces sp. PBR19, isolated from forest rhizosphere soil of Assam
An Actinomycetia isolate, designated as PBR19, was derived from the rhizosphere soil of Pobitora Wildlife Sanctuary (PWS), Assam, India. The isolate,...
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The effect of Toxoplasma gondii infection on galectin-9 expression in decidual macrophages contributing to dysfunction of decidual NK cells during pregnancy
BackgroundToxoplasma gondii infection causes adverse pregnancy outcomes by affecting the expression of immunotolerant molecules in decidual immune...
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Fecal microbiota composition is a better predictor of recurrent Clostridioides difficile infection than clinical factors in a prospective, multicentre cohort study
IntroductionClostridioides difficile infection (CDI) is the most common cause of antibiotic-associated diarrhoea. Fidaxomicin and fecal microbiota...
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Network analysis of gut microbial communities reveal key genera for a multiple sclerosis cohort with Mycobacterium avium subspecies paratuberculosis infection
BackgroundIn gut ecosystems, there is a complex interplay of biotic and abiotic interactions that decide the overall fitness of an individual....
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Epidemiology of biliary tract-associated bloodstream infections and adequacy of empiric therapy: an Australian population-based study
PurposeAlthough the biliary tract is a common source of invasive infections, the epidemiology of cholangitis- and cholecystitis-associated...
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A new geminialphasatellite associated with wheat dwarf virus identified in winter barley in France
Using a high-throughput sequencing (HTS) approach, we report the discovery of a new alphasatellite identified in a winter barley plant collected in...
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Real world community-based HIV Rapid Start Antiretroviral with B/F/TAF versus prior models of antiretroviral therapy start – the RoCHaCHa study, a pilot study
BackgroundThe rapid start of antiretroviral therapy (RSA) model initiates antiretroviral therapy (ART) as soon as possible after a new or preliminary...
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A review on the cultivation, bioactive compounds, health-promoting factors and clinical trials of medicinal mushrooms Taiwanofungus camphoratus, Inonotus obliquus and Tropicoporus linteus
Medicinal mushrooms, such as Taiwanofungus camphoratus , Inonotus obliquus , and Tropicoporus linteus , have been used in traditional medicine for...
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A small molecule compound targeting hemagglutinin inhibits influenza A virus and exhibits broad-spectrum antiviral activity
Influenza A virus (IAV) is a widespread pathogen that poses a significant threat to human health, causing pandemics with high mortality and...
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sciMET-cap: high-throughput single-cell methylation analysis with a reduced sequencing burden
DNA methylation is a key component of the mammalian epigenome, playing a regulatory role in development, disease, and other processes. Robust,...
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TFscope: systematic analysis of the sequence features involved in the binding preferences of transcription factors
Characterizing the binding preferences of transcription factors (TFs) in different cell types and conditions is key to understand how they...
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Mutational Improvement of the Lactobacillus delbrueckii subsp. lactis Biopreservation Potential
AbstractThe primary objective of this study was to develop tools and strategies aimed at enhancing the synthesis of hydrogen peroxide in Lactobacillus...
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Hepatitis B virus in Egypt: the whole story
Hepatitis B virus (HBV) infection is a significant global public health threat with variable geographical distribution. Chronic infection with HBV...
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Pathogenomics analysis of high-risk clone ST147 multidrug-resistant Klebsiella pneumoniae isolated from a patient in Egypt
BackgroundThe emergence of multi-drug-resistant Klebsiella pneumoniae (MDR-KP) represents a serious clinical health concern. Antibiotic resistance...
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Optimization of biotransformation processes of Camarosporium laburnicola to improve production yields of potent telomerase activators
BackgroundTelomerase activators are promising agents for the healthy aging process and the treatment/prevention of short telomere-related and...
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Liver X receptor inverse agonist SR9243 attenuates rheumatoid arthritis via modulating glycolytic metabolism of macrophages
Liver X receptors (LXRs) which link lipid metabolism and inflammation, were overexpressed in experimental rheumatoid arthritis (RA) rats as observed...
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An affordable detection system based on RT-LAMP and DNA-nanoprobes for avian metapneumovirus
AbstractAirborne animal viral pathogens can rapidly spread and become a global threat, resulting in substantial socioeconomic and health...
