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  1. Human Infant Fecal Microbiota Differentially Influences the Mucosal Immune Pathways Upon Influenza Infection in a Humanized Gnotobiotic Pig Model

    In this study, we evaluated the impact of human gut microbiota on the immune pathways in the respiratory tract using a gnotobiotic (Gn) piglet model....

    Jennifer Schrock, Ming Yan, ... Gourapura J. Renukaradhya in Current Microbiology
    Article Open access 14 July 2024
  2. Establishing Host–Virus Link Through Host Metabolism: Viral DNA SIP Validation Using T4 Bacteriophage and E. coli

    DNA Stable Isotope Probing is emerging as a potent methodology for investigating host–virus interactions, based on the essential reliance of viruses...

    Vuong Quoc Hoang Ngo, Maximilien Sotomski, ... Ariane Bize in Current Microbiology
    Article Open access 14 July 2024
  3. Mechanistic Investigation on the Antibacterial Activity of Biogenic Silver Nanoparticles Prepared Using Root Extract of Sarsaparilla and Demonstrated their In Vivo Efficacy in Zebrafish Model

    Antibiotic success rates are decreasing as drug-resistant bacteria become more prevalent, prompting the development of new therapeutic drugs. Herein,...

    Karnan Singaravelu Dharshini, Fuad Ameen, Veerappan Anbazhagan in Current Microbiology
    Article 14 July 2024
  4. Emerging Cases of Cat-Transmitted Sporotrichosis Driven by Sporothrix brasiliensis in Northeast Brazil

    Cat-transmitted sporotrichosis is caused by the emerging fungal pathogen Sporothrix brasiliensis and constitutes a significant public health issue...

    Pollyanne Raysa Fernandes de Oliveira, Jamile Ambrósio de Carvalho, ... Rinaldo Aparecido Mota in Mycopathologia
    Article 14 July 2024
  5. Early oxidative stress and DNA damage in Aβ-burdened hippocampal neurons in an Alzheimer’s-like transgenic rat model

    Oxidative stress is a key contributor to AD pathology. However, the earliest role of pre-plaque neuronal oxidative stress, remains elusive. Using...

    Morgan K. Foret, Chiara Orciani, ... Sonia Do Carmo in Communications Biology
    Article Open access 14 July 2024
  6. Development of Rapid Disk Diffusion Device Using Laser Speckle Formation Technology for Rapid Antimicrobial Susceptibility Testing

    The escalation of antimicrobial resistance (AMR) due to the excessive and inappropriate use of antimicrobials has prompted the urgent need for more...

    Jaehyeon Lee, Jun Han Lee, ... Jeong Su Park in Current Microbiology
    Article Open access 14 July 2024
  7. Optimizing Real-Time PCR for Accurate Identification and Quantification of Common Probiotic Bacteria in Iranian Probiotic Dairy Products

    The effectiveness of probiotics for health depends on the strain type and dosage. In this study, we endeavored to establish a robust quantitative...

    Setayesh Zamanpour, Vida Eraghi, ... Asma Afshari in Indian Journal of Microbiology
    Article 14 July 2024
  8. m1A demethylase Alkbh3 regulates neurogenesis through m1A demethylation of Mmp15 mRNA

    Background

    N 1 -Methyladenosine (m 1 A) is an abundant modification of transcripts regulating mRNA structure and translation efficiency. However, the...

    Huan Wang, Linjie **e, ... Aiguo Xuan in Cell & Bioscience
    Article Open access 14 July 2024
  9. Butyricimonas faecihominis: an atypically resistant bacterium implicated in abscess formation - a case report

    Background

    This case report presents a unique instance of abscesses with an uncommon pathogen isolated from blood cultures.

    Case presentation ...
    Lukas Wessendorf, Tobias Brezina, ... Alessa L. Boschert in BMC Infectious Diseases
    Article Open access 14 July 2024
  10. A versatile functional interaction between electrically silent KV subunits and KV7 potassium channels

    Voltage-gated K + (K V ) channels govern K + ion flux across cell membranes in response to changes in membrane potential. They are formed by the assembly...

    Vijay Renigunta, Nermina Xhaferri, ... Moritz Lindner in Cellular and Molecular Life Sciences
    Article Open access 14 July 2024
  11. SUMOylation of nuclear receptor Nor1/NR4A3 coordinates microtubule cytoskeletal dynamics and stability in neuronal cells

    Background

    Nor1/NR4A3 is a member of the NR4A subfamily of nuclear receptors that play essential roles in regulating gene expression related to...

    Jonathan Gagnon, Véronique Caron, André Tremblay in Cell & Bioscience
    Article Open access 13 July 2024
  12. Identification of volatile metabolites produced from levodopa metabolism by different bacteria strains of the gut microbiome

    Interspecies pathways in the gut microbiome have been shown to metabolize levodopa, the primary treatment for Parkinson’s disease, and reduce its...

    Taylor Pennington, Jarrett Eshima, Barbara S. Smith in BMC Microbiology
    Article Open access 13 July 2024
  13. C4-like Sesuvium sesuvioides (Aizoaceae) exhibits CAM in cotyledons and putative C4-like + CAM metabolism in adult leaves as revealed by transcriptome analysis

    Background

    The co-occurrence of C 4 and CAM photosynthesis in a single species seems to be unusual and rare. This is likely due to the difficulty in...

    Christian Siadjeu, Gudrun Kadereit in BMC Genomics
    Article Open access 13 July 2024
  14. Increasing the efficiency of CRISPR/Cas9-mediated genome editing in the citrus postharvest pathogen Penicillium digitatum

    Background

    Penicillium digitatum is a fungal plant pathogen that causes the green mold disease in harvested citrus fruits. Due to its economical...

    Carolina Ropero-Pérez, Jose F. Marcos, ... Sandra Garrigues in Fungal Biology and Biotechnology
    Article Open access 13 July 2024
  15. Preclinical and clinical advances to overcome hypoxia in glioblastoma multiforme

    Glioblastoma multiforme (GBM) is the most common adult primary brain tumor. The standard clinical treatment of GBM includes a maximal surgical...

    Jolie Bou-Gharios, Georges Noël, Hélène Burckel in Cell Death & Disease
    Article Open access 13 July 2024
  16. Lysinibacillus pinottii sp. nov., a novel species with anti-mosquito and anti-mollusk activity

    An isolate of a Gram-positive, strictly aerobic, motile, rod-shaped, endospore forming bacterium was originally isolated from soil when screening and...

    Christopher A. Dunlap, Eric T. Johnson, ... Ephantus J. Muturi in Antonie van Leeuwenhoek
    Article 13 July 2024
  17. Effects of warm oceanographic anomalies on the foraging variability of northern elephant seals

    Evaluation of stable carbon (δ 13 C) and nitrogen (δ 15 N) isotopes in marine organisms over time addresses how environmental variability (e.g., El...

    Eunice D. Rodríguez-Rafael, Fernando R. Elorriaga-Verplancken, ... Felipe Galván-Magaña in Marine Biology
    Article 13 July 2024
  18. Enhancing monolignol ferulate conjugate levels in poplar lignin via OsFMT1

    Background

    The phenolic polymer lignin is one of the primary chemical constituents of the plant secondary cell wall. Due to the inherent plasticity of...

    Faride Unda, Lisanne de Vries, ... Shawn D. Mansfield in Biotechnology for Biofuels and Bioproducts
    Article Open access 13 July 2024
  19. Age-related dysregulation of CXCL9/10 in monocytes is linked to impaired innate immune responses in a mouse model of Staphylococcus aureus osteomyelitis

    Background

    Age-associated impairments in innate immunity are believed to be a causative factor responsible for severe pathogenesis of Staphylococcus...

    Yihuang Lin, Mankai Yang, ... **anrong Zhang in Cellular and Molecular Life Sciences
    Article Open access 13 July 2024
  20. CRISPR screens in 3D tumourspheres identified miR-4787-3p as a transcriptional start site miRNA essential for breast tumour-initiating cell growth

    Our study employs pooled CRISPR screens, integrating 2D and 3D culture models, to identify miRNAs critical in Breast Cancer (BC) tumoursphere...

    Tom Stiff, Salih Bayraktar, ... Leandro Castellano in Communications Biology
    Article Open access 13 July 2024
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