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Admiration and motivation: key factors in managing PTSD among firefighters
Post-traumatic stress disorder (PTSD) presents a significant challenge for firefighters. While research suggests that admiration may have a positive...
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Association between organophosphorus insecticides exposure and osteoarthritis in patients with arteriosclerotic cardiovascular disease
BackgroundOrganic phosphorus insecticides (OPPs) are a class of environmental pollutants widely used worldwide with potential human health risks. We...
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Detection and disclosure of workplace mental health challenges: an exploratory study from India
Workplace mental health challenges have emerged as a significant concern post-pandemic. Despite this, the pervasive stigma surrounding mental illness...
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Impact of secondhand smoke on air quality in partially enclosed outdoor hospitality venues: a review
BackgroundSmoking is a leading cause of premature mortality and morbidity globally. The pollutants generated from smoke are not only harmful to...
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Preclinical and clinical advances to overcome hypoxia in glioblastoma multiforme
Glioblastoma multiforme (GBM) is the most common adult primary brain tumor. The standard clinical treatment of GBM includes a maximal surgical...
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Assessing risk for severe domestic violence and related homicides perpetrated by partners and in-laws: adapted danger assessments for women in abusive relationships in India
Despite domestic violence and related homicides perpetrated by partners and/or in-laws being a significant public health problem in India, there are...
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Gastrointestinal parasites of Wolffsohn’s viscacha (Chinchillidae: Lagidium wolffsohni), an endemic rodent species from the wild Patagonia
Parasites are ubiquitous in wildlife populations and have a profound impact on population dynamics. Interest in parasites of wildlife has increased...
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The eEF2 kinase coordinates the DNA damage response to cisplatin by supporting p53 activation
Eukaryotic elongation factor 2 (eEF2) kinase (eEF2K) is a stress-responsive hub that inhibits the translation elongation factor eEF2, and...
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Reassortment incompetent live attenuated and replicon influenza vaccines provide improved protection against influenza in piglets
Swine influenza A viruses (swIAV) cause an economically important respiratory disease in modern pig production. Continuous virus transmission and...
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IL-4/IL-4R axis signaling drives resistance to immunotherapy by inducing the upregulation of Fcγ receptor IIB in M2 macrophages
In recent years, immunotherapy, particularly PD-1 antibodies, have significantly enhanced the outcome of gastric cancer patients. Despite these...
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The ubiquitin-like protein UBTD1 promotes colorectal cancer progression by stabilizing c-Myc to upregulate glycolysis
Dysfunction of the ubiquitin-proteasome system (UPS) is involved in the pathogenesis of various malignancies including colorectal cancer (CRC)....
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Prevalence of interarm blood pressure difference is notably higher in women; the Viborg population-based screening program (VISP)
BackgroundBilateral blood pressure (BP) measurement is important in cardiovascular prevention for identifying systolic interarm BP difference (IAD)...
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“Older people will die of old age. I’ll die of climate change”: engaging children and young people in climate decision making for public health
BackgroundThe climate crisis is a significant risk to the health and wellbeing of children, young people, and future generations. While there are...
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Multimodal training protocols on unstable rather than stable surfaces better improve dynamic balance ability in older adults
BackgroundThere has been growing interest in using unstable devices in training protocols. This study aimed to assess the effectiveness of two...
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Orchestration of antiviral responses within the infected central nervous system
Many newly emerging and re-emerging viruses have neuroinvasive potential, underscoring viral encephalitis as a global research priority. Upon entry...
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Nuclear alpha-synuclein accelerates cell senescence and neurodegeneration
BackgroundThe progression of Parkinson’s disease (PD) is related to ageing. The accumulation of nuclear alpha-synuclein (α-syn) may accelerate the...
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Physical activity is associated with lower mortality in adults with obesity: a systematic review with meta-analysis
BackgroundObesity is a complex chronic disease associated with several adverse health outcomes that increase mortality risk. Physical activity (PA)...
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AXDND1 is required to balance spermatogonial commitment and for sperm tail formation in mice and humans
Dynein complexes are large, multi-unit assemblies involved in many biological processes via their critical roles in protein transport and axoneme...
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Specific CD4+ T cell phenotypes associate with bacterial control in people who ‘resist’ infection with Mycobacterium tuberculosis
A subset of individuals exposed to Mycobacterium tuberculosis ( Mtb ) that we refer to as ‘resisters’ (RSTR) show evidence of IFN-γ − T cell responses...
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Increased ONECUT2 induced by Helicobacter pylori promotes gastric cancer cell stemness via an AKT-related pathway
Helicobacter pylori (HP) infection initiates and promotes gastric carcinogenesis. ONECUT2 shows promise for tumor diagnosis, prognosis, and...
