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Glycogenolysis-Induced Astrocytic Ser**1 Expression Regulates Neuroinflammatory Effects on Hippocampal neuron
The bacterial pathogen, lipopolysaccharide (LPS), elicits microglial response and induces cytokine secretion that subsequently activates astrocytes....
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Greater Self-reported Health is Associated with Lower Disgust: Evidence for Individual Calibration of the Behavioral Immune System
A key theoretical component of the behavioral immune system is its functional flexibility, where an individual’s reaction to pathogenic stimuli is...
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A possible role of lncRNA MEG3 and lncRNA MAFG-AS1 on miRNA 147-b in the pathogenesis of Behcet’s disease
Behcet’s disease (BD) is a multisystem disease with altered Toll-like receptors (TLRs) on macrophages. Long noncoding RNA Maternally expressed gene 3...
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Dysregulated Wnt/β-catenin signaling confers resistance to cuproptosis in cancer cells
Cuproptosis is characterized by the aggregation of lipoylated enzymes of the tricarboxylic acid cycle and subsequent loss of iron-sulfur cluster...
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Reactive oxygen species and depolarization the inner mitochondrial membrane under effect of synthetic auxin herbicides in plant cell culture of Arabidopsis thaliana L.
The cytotoxic effect of synthetic analogs of auxins, namely 2.4-D and clopyralid on heterotrophic cell suspension culture of Arabidopsis thaliana ,...
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Goat weed (Ageratum conyzoides L.): A biological threat to plant diversity in Eastern Ghats of India
The Kunming–Montreal Global Biodiversity Framework (GBF) is a recently signed protocol by the conference of the parties (COP 15) with an aim to...
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Efficacy and safety of oral semaglutide monotherapy vs placebo in a predominantly Chinese population with type 2 diabetes (PIONEER 11): a double-blind, Phase IIIa, randomised trial
Aims/hypothesisThe aim of this study was to evaluate the efficacy and safety of oral semaglutide monotherapy vs placebo in a predominantly Chinese...
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CRISPR/Cas9-mediated genome editing technique to control fall armyworm (Spodoptera frugiperda) in crop plants with special reference to maize
Fall Armyworm imposes a major risk to agricultural losses. Insecticides have historically been used to manage its infestations, but it eventually...
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Strategies for modeling aging and age-related diseases
The ability to reprogram patient-derived-somatic cells to IPSCs (Induced Pluripotent Stem Cells) has led to a better understanding of aging and...
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An Investigation on the Present Status of Wetlands in Majuli River Island; The World Largest River Island and Its Fishery Resources
Wetlands are widely known for its distinctive and most diverse ecosystems in the world. Assam is blessed with number of lentic systems . The beels are...
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Exploratory Mass Spectrometry of Cerebrospinal Fluid from Persons with Autopsy-Confirmed LATE-NC
Common neuropathologies associated with dementia include Alzheimer’s disease neuropathologic change (ADNC) and limbic-predominant age-related TDP-43...
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MicroRNA-21 modulates brown adipose tissue adipogenesis and thermogenesis in a mouse model of polycystic ovary syndrome
BackgroundPolycystic ovary syndrome (PCOS), the most common endocrine disorder in premenopausal women, is associated with increased obesity,...
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Predatory Behavior of Wasp Species, Antagonistic Defense Mechanism of Apis mellifera Honey Bees and Effective Wasp Management in Apiaries
To manage bee-wasp species interaction, knowledge of wasp predaceous behavior and honey bees’ defense mechanism are of utmost importance. It is an...
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Genome-wide identification and expression analysis of the SOD gene family under biotic and abiotic stresses in sweet orange
Superoxide dismutase (SOD) protects plants from biotic and abiotic stress-induced reactive oxygen species toxicity and is extensively involved in...
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Investigating the Impact of Intracerebroventricular Streptozotocin on Female Rats with and without Ovaries: Implications for Alzheimer’s Disease
To contribute to research on female models of Alzheimer’s disease (AD), our aim was to study the effect of intracerebroventricular (ICV) injection of...
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Modulation of miR-155-5p signalling via 5-ASA for the prevention of high microsatellite instability: an in vitro study using human epithelial cell lines
5-aminosalicylic acid (5-ASA) is a first-line treatment for maintaining colitis remission. It is a highly effective, safe, and well-tolerated drug...
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Association between dietary (poly)phenol intake and the ATHLOS Healthy Ageing Scale in the Polish arm of the HAPIEE study
Inverse association between (poly)phenol intake and age-related disorders has been demonstrated; however, little is known whether they affect...
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Unveiling the mechanism of essential oil action against skin pathogens: from ancient wisdom to modern science
Essential oils are among the most well-known phyto-compounds, and since ancient times, they have been utilized in medicine. Over 100 essential oils...
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Influence of sustained mild dehydration on thermoregulatory and cognitive functions during prolonged moderate exercise
PurposeThe current study investigated whether sustained mild dehydration affects thermoregulatory function and cognitive performance during prolonged...
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LINC01133 promotes pancreatic ductal adenocarcinoma epithelial–mesenchymal transition mediated by SPP1 through binding to Arp3
Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease with limited treatment methods. Long non-coding RNAs (lncRNAs) have been found involved...