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  1. Intracranial dissemination of Klebsiella pneumoniae originating from pulmonary infection: a case report

    Background

    Metastatic brain abscesses caused by Klebsiella pneumoniae are extremely rare but life-threatening conditions. To depict a unique case of...

    Ghazaleh Jamalipoursufi, Ali Hajihashemi, ... Mahsa Geravandi in Journal of Medical Case Reports
    Article Open access 14 July 2024

  2. PIM1/NF-κB/CCL2 blockade enhances anti-PD-1 therapy response by modulating macrophage infiltration and polarization in tumor microenvironment of NSCLC

    Elevated infiltration of tumor-associated macrophages (TAMs) drives tumor progression and correlates with poor prognosis for various tumor types. Our...

    **uqiong Chen, **g Zhou, ... Richeng Jiang in Oncogene
    Article 14 July 2024

  3. Outcomes of patients undergoing third hematopoietic cell transplantation for hematologic malignancies

    With advancements in novel therapeutics, it is unclear whether third hematopoietic cell transplantation (HCT3) has a place in the treatment of...

    Emily R. Cox, Corinne Summers, ... Monica S. Thakar in Annals of Hematology
    Article 14 July 2024

  4. Loss of sheen in Oguchi disease following short wavelength exposure

    Haseeb N. Akhtar, Luke Nicholson, ... Omar A. Mahroo in Eye
    Article Open access 14 July 2024

  5. Identifying early symptoms associated with a diagnosis of childhood, adolescent and young adult cancers: a population-based nested case-control study

    Background

    Childhood, teenage and young adult (CTYA, 0–24 years) cancers are rare and diverse, making timely diagnosis challenging. We aim to explore...

    D. Saatci, J. Oke, ... J. Hippisley-Cox in British Journal of Cancer
    Article Open access 14 July 2024

  6. Altered RNA export by SF3B1 mutants confers sensitivity to nuclear export inhibition

    SF3B1 mutations frequently occur in cancer yet lack targeted therapies. Clinical trials of XPO1 inhibitors, selinexor and eltanexor, in high-risk...

    Sana Chaudhry, Felipe Beckedorff, ... Justin Taylor in Leukemia
    Article Open access 13 July 2024

  7. Doing a double take: when transthoracic echocardiography fails for mitral valve annuloplasty ring endocarditis with Streptococcus pyogenes: a case report

    Background

    This case highlights several complications of a late and rare presentation of culture-negative Streptococcus pyogenes endocarditis of a...

    Jonathan K. Schilling, Robert Tungate, ... Antonio H. Frangieh in Journal of Medical Case Reports
    Article Open access 13 July 2024

  8. Dietary salt promotes cognitive impairment through repression of SIRT3/PINK1-mediated mitophagy and fission

    Dietary salt is increasingly recognized as an independent risk factor for cognitive impairment. However, the exact mechanisms are not yet fully...

    Haixia Fan, Minghao Yuan, ... Zhiyou Cai in Molecular and Cellular Biochemistry
    Article 13 July 2024

  9. Analysis of Oncology and Radiation Therapy Representation on the National Board of Medical Examiners Official Practice Material for the United States National Standardized Medical Board Examinations

    Radiation therapy (RT) is a critical component of multidisciplinary cancer care, but has inconsistent curricular exposure. We characterize the...

    Mary T. Mahoney, Lauren C. Linkowski, ... Malcolm D. Mattes in Journal of Cancer Education
    Article Open access 13 July 2024

  10. Death anxiety among caregivers of patients with advanced cancer: a cross-sectional survey

    Purpose

    This study aimed to investigate death anxiety (DA) in caregivers of patients with advanced cancer and identify associated factors in the...

    Li Ying, Duan Yuyu, ... Zhou Zhihuan in Supportive Care in Cancer
    Article 13 July 2024

  11. Physiological and cellular mechanisms of ischemic preconditioning microRNAs-mediated in underlying of ischemia/reperfusion injury in different organs

    Ischemia–reperfusion (I/R) injury, as a pathological phenomenon, takes place when blood supply to an organ is disrupted and then aggravated during...

    Izadpanah Gheitasi, Ghaidafeh Akbari, Feryal Savari in Molecular and Cellular Biochemistry
    Article 13 July 2024

  12. Key genes and molecular mechanisms related to Paclitaxel Resistance

    Paclitaxel is commonly used to treat breast, ovarian, lung, esophageal, gastric, pancreatic cancer, and neck cancer cells. Cancer recurrence is...

    Adel I. Alalawy in Cancer Cell International
    Article Open access 13 July 2024

  13. Carbon-ion radiotherapy alone vs. standard dose photon radiation with carbon-ion radiotherapy boost for high-grade gliomas: a retrospective study

    Background

    This study aimed to compare the survival outcome and side effects in patients with primary high-grade glioma (HGG) who received carbon ion...

    **aoJun Li, YanShan Zhang, ... Faxin Wen in BMC Cancer
    Article Open access 13 July 2024

  14. Safety and Efficacy of Covered Self-Expandable Metallic Stent for Choledochojejunal Anastomotic Stricture: A Multi-Center Retrospective Cohort Study

    Background

    Benign choledochojejunal anastomotic stricture (CJS) is a complication of pancreaticoduodenectomy and choledochojejunostomy. Typically...

    Yuhei Iwasa, Takuji Iwashita, ... Masahito Shimizu in Digestive Diseases and Sciences
    Article 13 July 2024

  15. Deep learning model based on endoscopic images predicting treatment response in locally advanced rectal cancer undergo neoadjuvant chemoradiotherapy: a multicenter study

    Purpose

    Neoadjuvant chemoradiotherapy has been the standard practice for patients with locally advanced rectal cancer. However, the treatment response...

    Junhao Zhang, Ruiqing Liu, ... Yun Lu in Journal of Cancer Research and Clinical Oncology
    Article Open access 13 July 2024

  16. Peripheral blood immune parameters, response, and adverse events after neoadjuvant chemotherapy plus durvalumab in early-stage triple-negative breast cancer

    Purpose

    We evaluated T- and B-cell receptor (TCR and BCR) repertoire diversity and 38 serum cytokines in pre- and post-treatment peripheral blood of...

    Julia Foldi, Kim R. M. Blenman, ... Lajos Pusztai in Breast Cancer Research and Treatment
    Article 13 July 2024

  17. Association of oral mucositis induced by anthracycline-cyclophosphamide and subsequent docetaxel treatment for perioperative breast cancer

    Purpose

    Anthracycline-cyclophosphamide followed by docetaxel-containing chemotherapy is effective for perioperative breast cancer treatment. However,...

    Yoshitaka Saito, Yoh Takekuma, ... Mitsuru Sugawara in Supportive Care in Cancer
    Article 13 July 2024

  18. Hyponatremia Is Associated with Mortality in Acute Pancreatitis Patients

    Background

    Disorders of serum sodium are common among general patients and are associated with poor outcomes. The prognostic value of serum sodium...

    Liqing Song, Wen Tang, ... Ying Xu in Digestive Diseases and Sciences
    Article 13 July 2024

  20. BRAF-mutant mismatch repair deficient invasive colon cancer regressing to sessile serrated lesion

    A 69-year-old female was presented with a history of sigmoid colon cancer, uterine cancer, and intrahepatic carcinomas. After computed tomography...

    Kenshi Matsuno, Hideaki Miyamoto, ... Yasuhito Tanaka in Clinical Journal of Gastroenterology
    Article 13 July 2024
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