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Hodgkin lymphoma and liquid biopsy: a story to be told
Hodgkin lymphoma (HL) represents a neoplasm primarily affecting adolescents and young adults, necessitating the development of precise diagnostic and...
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Impact of USMLE Step 1 transition to pass/fail scoring system on medical students’ anxiety, sleep quality, and burnout
IntroductionOriginally designed to evaluate the application of foundational scientific knowledge in clinical contexts, the United States Medical...
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Hypermethylated TAGMe as a universal-cancer-only methylation marker and its application in diagnosis and recurrence monitoring of urothelial carcinoma
BackgroundUrothelial carcinoma (UC) is the second most common urological malignancy. Despite numerous molecular markers have been evaluated during...
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SMS-based interventions for improving child and adolescent vaccine coverage and timeliness: a systematic review
BackgroundThe aim of this review was to investigate the impact of short message service (SMS)-based interventions on childhood and adolescent vaccine...
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Peroxiredoxin 6 Protects Pulmonary Epithelial Cells From Cigarette-related Ferroptosis in Chronic Obstructive Pulmonary Disease
Peroxiredoxin 6 (PRDX6) has a protective effect on pulmonary epithelial cells against cigarette smoke (CS)-induced ferroptosis. This study...
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Associations between accelerometer-measured physical activity and sedentary behaviour with physical function among older women: a cross-sectional study
BackgroundThis study aimed to investigate the relationships between accelerometer-measured physical activity (PA) and sedentary behaviour (SB) with...
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miR-146a and miR-155 as promising biomarkers for prognosis and diagnosis of multiple sclerosis: systematic review
BackgroundSmall RNA molecules known as microRNAs (miRNAs) regulate gene expression during the post-translational steps. miRNAs are essential for many...
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Long-term comparison of renal and metabolic outcomes after sodium–glucose co-transporter 2 inhibitor or glucagon-like peptide-1 receptor agonist therapy in type 2 diabetes
BackgroundRenal outcomes in patients with type 2 diabetes following treatment with sodium–glucose co-transporter-2 inhibitors (SGLT2is) or...
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Benzodiazepine use in relation to long-term dementia risk and imaging markers of neurodegeneration: a population-based study
BackgroundBenzodiazepine use is common, particularly in older adults. Benzodiazepines have well-established acute adverse effects on cognition, but...
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Inappropriate treatment of pulmonary aspergillosis caused by Aspergillus flavus in susceptible pediatric patients: a case series
BackgroundPulmonary aspergillosis is a prevalent opportunistic fungal infection that can lead to mortality in pediatric patients with underlying...
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Neuroimmune crosstalk
Cardiovascular diseases are the leading cause of death worldwide. Pathophysiologically, metabolic and inflammatory processes contribute substantially...
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Effect of norepinephrine and phenylephrine on prothrombotic response in patients undergoing cesarean section under spinal anesthesia: protocol for a randomized, double-blind, controlled study
BackgroundNorepinephrine and phenylephrine are commonly used vasoactive drugs to treat hypotension during the perioperative period. The increased...
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Comparative analysis of genetic risk scores for predicting biochemical recurrence in prostate cancer patients after radical prostatectomy
BackgroundIn recent years, Genome-Wide Association Studies (GWAS) has identified risk variants related to complex diseases, but most genetic variants...
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A Comprehensive Overview of NF1 Mutations in Iranian Patients
Neurofibromatosis type 1 (NF1) is a genetic disorder caused by mutations in the NF1 gene. This disorder shows nearly complete penetrance and high...
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Assessment of the Efficacy and Durability of IncobotulinumtoxinA in the Treatment of the Upper Face in Adult Women
IntroductionIncobotulinumtoxinA (Xeomin®) is used in the treatment of dynamic wrinkles and the aesthetic repositioning of facial structures. The...
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Association Between Natural Hair Color, Race, and Alopecia
IntroductionLimited epidemiologic data has suggested direct associations between hair pigment, race, and incidence of alopecia areata (AA). Here, we...
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PCSK9 Inhibitors and Infection-Related Adverse Events: A Pharmacovigilance Study Using the World Health Organization VigiBase
AimsProtein convertase subtilisin/kexin type 9 inhibitors (PCSK9i) are novel lipid-lowering agents used in patients with cardiovascular disease....
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A discrete subpopulation of PFC-LHb neurons govern cocaine place preference
Addiction is a complex behavioral disorder characterized by compulsive drug-seeking and drug use despite harmful consequences. The prefrontal cortex...
