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Indicated Prevention for Children Screened in Routine Health Care: Effectiveness of a Social Skills Program on Social Anxiety and Depressive Symptoms
Social anxiety is common in childhood and potentially transitions into clinical disorders including depression. The present study aimed to examine...
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The parasubthalamic nucleus refeeding ensemble delays feeding initiation and hastens water drinking
The parasubthalamic nucleus (PSTN) is activated by refeeding after food deprivation and several PSTN subpopulations have been shown to suppress...
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New horizons for the role of selenium on cognitive function: advances and challenges
Cognitive deficits associated with oxidative stress and the dysfunction of the central nervous system are present in some neurodegenerative diseases,...
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Context-dependent reduction in corticomuscular coupling for balance control in chronic stroke survivors
Balance control is an important indicator of mobility and independence in activities of daily living. How the functional coupling between the cortex...
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Evidence of bottom-up homeostatic modulation induced taVNS during emotional and Go/No-Go tasks
Bilateral transcutaneous auricular vagus nerve stimulation (taVNS) - a non-invasive neuromodulation technique – has been investigated as a safe and...
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A skin-specific α-Synuclein seeding amplification assay for diagnosing Parkinson’s disease
The seeding amplification assay (SAA) has recently emerged as a valuable tool for detecting α-synuclein (αSyn) aggregates in various clinically...
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Unraveling psilocybin’s therapeutic potential: behavioral and neuroplasticity insights in Wistar-Kyoto and Wistar male rat models of treatment-resistant depression
RationaleOur study aimed to unravel the unknown mechanisms behind the exceptional efficacy of Psilocybin (PSI) in treating treatment-resistant...
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From movement to motivation: a proposed framework to understand the antidepressant effect of exercise
Depression is the leading cause of disability worldwide, exerting a profound negative impact on quality of life in those who experience it....
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“There is No Help:” Caregiver Perspectives on Service Needs for Adolescents and Adults with Profound Autism
The underrepresentation of individuals with profound autism (who require 24/7 access to care) in autism research has resulted in limited knowledge...
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Standardized reporting for Head CT Scans in patients suspected of traumatic brain injury (TBI): An international expert endeavor
Background and purposeTraumatic brain injury (TBI) is a major source of health loss and disability worldwide. Accurate and timely diagnosis of TBI is...
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Fisetin ameliorates polycystic ovary syndrome in rats via a mechanistic modulation of AMP-activated protein kinase and SIRT1 molecular pathway
Fisetin , a polyphenolic flavonoid, exhibits numerous pharmacological activities against metabolic syndromes. The present research aims to explore the...
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Principled distillation of UK Biobank phenotype data reveals underlying structure in human variation
Data within biobanks capture broad yet detailed indices of human variation, but biobank-wide insights can be difficult to extract due to complexity...
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Extension of efficacy range for targeted malaria-elimination interventions due to spillover effects
Malaria-elimination interventions aim to extinguish hotspots and prevent transmission to nearby areas. Here, we re-analyzed a cluster-randomized...
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Striatal projection neurons coexpressing dopamine D1 and D2 receptors modulate the motor function of D1- and D2-SPNs
The role of the striatum in motor control is commonly assumed to be mediated by the two striatal efferent pathways characterized by striatal...
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A measure of reliability convergence to select and optimize cognitive tasks for individual differences research
Surging interest in individual differences has faced setbacks in light of recent replication crises in psychology, for example in brain-wide...
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Real-world data of in-hospital administration of alglucosidase alfa in French patients with Pompe disease: results from the National Claims Database
IntroductionPompe disease is caused by a rare biallelic mutation in the GAA gene resulting in acid α-glucosidase deficiency and glycogen...
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Vitamin D, chronic pain, and depression: linear and non-linear Mendelian randomization analyses
Vitamin D deficiency has been linked to various chronic pain conditions. However, randomized trials of vitamin D supplementation have had mixed...
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Suicide attempts and correlates among in-school adolescents in Benin City, Nigeria
We aim to add to the literature on suicidality in Africa by estimating the prevalence and exploring the behavioural correlates of suicide attempts...
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Nucleus accumbens ghrelin signaling controls anxiety-like behavioral response to acute stress
BackgroundAnxiety disorders are one of the most common mental disorders. Ghrelin is a critical orexigenic brain-gut peptide that regulates food...
