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Efficient leather spreading operations by dual-arm robotic systems
To achieve precise gras** and spreading of irregular sheet-like soft objects (such as leather) by robots, this study addresses several challenges,...
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Large-scale whole-exome sequencing analyses identified protein-coding variants associated with immune-mediated diseases in 350,770 adults
The genetic contribution of protein-coding variants to immune-mediated diseases (IMDs) remains underexplored. Through whole exome sequencing of 40...
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I/O-efficient iterative matrix inversion with photonic integrated circuits
Photonic integrated circuits have been extensively explored for optical processing with the aim of breaking the speed and energy...
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JWH-182: a safe and effective synthetic cannabinoid for chemotherapy-induced neuropathic pain in preclinical models
Chemotherapy-induced neuropathic pain (CINP), a condition with unmet treatment needs, affects over half of cancer patients treated with...
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A One Health framework for exploring zoonotic interactions demonstrated through a case study
The eco-epidemiology of zoonoses is often oversimplified to host-pathogen interactions while findings derived from global datasets are rarely...
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Impact of bedaquiline regimen on the treatment success rates of multidrug-resistant tuberculosis patients in Egypt
Bedaquiline (BDQ), an innovative anti-tuberculous (TB) agent, has attracted attention for its potential effectiveness against drug-resistant TB. This...
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Temporal dynamics of climate change exposure and opportunities for global marine biodiversity
Climate change is exposing marine species to unsuitable temperatures while also creating new thermally suitable habitats of varying persistence....
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Efficient and reproducible generation of human iPSC-derived cardiomyocytes and cardiac organoids in stirred suspension systems
Human iPSC-derived cardiomyocytes (hiPSC-CMs) have proven invaluable for cardiac disease modeling and regeneration. Challenges with quality,...
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Laboratory infrared spectra and fragmentation chemistry of sulfur allotropes
Sulfur is one of six life-essential elements, but its path from interstellar clouds to planets and their atmospheres is not well known. Astronomical...
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Single-cell multiomics reveals ENL mutation perturbs kidney developmental trajectory by rewiring gene regulatory landscape
How disruptions to normal cell differentiation link to tumorigenesis remains incompletely understood. Wilms tumor, an embryonal tumor associated with...
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Sustained North Atlantic warming drove anomalously intense MIS 11c interglacial
The Marine Isotope Stage (MIS) 11c interglacial and its preceding glacial termination represent an enigmatically intense climate response to...
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LINE1-mediated epigenetic repression of androgen receptor transcription causes androgen insensitivity syndrome
Androgen insensitivity syndrome (AIS) is a difference of sex development (DSD) characterized by different degrees of undervirilization in individuals...
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Fabrication, characterization and numerical validation of a novel thin-wall hydrogel vessel model for cardiovascular research based on a patient-specific stenotic carotid artery bifurcation
In vitro vascular models, primarily made of silicone, have been utilized for decades for studying hemodynamics and supporting the development of...
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Association between the serum uric acid/serum creatinine ratio and cognitive function in older adults: NHANES in the United States
Cognitive impairment can potentially become a significant health concern in older adults. However, early effective diagnostic methods are still...
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Prenatal genetic diagnosis of fetuses with dextrocardia using whole exome sequencing in a tertiary center
To evaluate the genetic etiology of fetal dextrocardia, associated ultrasound anomalies, and perinatal outcomes, we investigated the utility of whole...
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Simultaneous production of syngas and carbon nanotubes from CO2/CH4 mixture over high-performance NiMo/MgO catalyst
Direct conversion of biogas via the integrative process of dry reforming of methane (DRM) and catalytic methane decomposition (CDM) has received a...
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Effect of ABCB1 most frequent polymorphisms on the accumulation of bictegravir in recombinant HEK293 cell lines
Bictegravir, a key second-generation integrase strand transfer inhibitor in the treatment of HIV, is subject to active efflux transport mediated by...
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An efficient learning based approach for automatic record deduplication with benchmark datasets
With technological innovations, enterprises in the real world are managing every iota of data as it can be mined to derive business intelligence...
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Impact of corrupt admission on the mental health of Chinese adolescents
Through preferential treatment by education officials or through bribery, some adolescents can obtain admission to a junior high school. However, it...