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A Mathematical Model for Fibrous Dysplasia: The Role of the Flow of Mutant Cells
Fibrous dysplasia (FD) is a mosaic non-inheritable genetic disorder of the skeleton in which normal bone is replaced by structurally unsound...
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Black swans swimming in product streams: method for including unplanned events in life cycle assessment
IntroductionUnplanned events such as accidents and more massive black-swan events are contingent to modern technology. However, varying approaches...
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Thalassospira aquimaris sp. nov. and Winogradskyella marincola sp. nov. two marine bacteria isolated from an agar-degrading co-culture
Two novel Gram-stain-negative, aerobic, and non-motile strains, designated FZY0004 T and YYF002 T , were isolated from an agar-degrading co-culture,...
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Inexpensive and colorimetric RNA detection at ambient temperature with a cell-free protein synthesis platform
While many proposals of paper-based diagnostics utilize cell-free gene expression systems, these assays oftentimes suffer from the need for...
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Redundancy in microbiota-mediated suppression of the soybean cyst nematode
BackgroundSoybean cyst nematodes (SCN) as animal parasites of plants are not usually interested in killing the host but are rather focused on...
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Cattleya attenboroughiana (Orchidaceae: Laeliinae): a new species from the Diamantina Plateau, Minas Gerais, Brazil
A new species of Cattleya ser. Parviflorae (Orchidaceae) is here described from the campos rupestres of the Diamantina Plateau, part of the Espinhaço...
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Influence of Protein on Calcium Bioaccessibility with Phytic Acid in Milled By-Product Fractions of Pulses
Pulses by-products are nutrient-dense which could serve as an unconventional plant-based protein source. Furthermore, given the higher prevalence of...
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Prophylactic Effect and Antiulcerogenic Potential of Probiotic Lactiplantibacillus plantarum E1K2R2 and its Exopolysaccharide Against Ibuprofen-Induced Acute Gastric Ulcer
Lactiplantibacillus plantarum ( Lpb. plantarum ), as a safe probiotic microorganism, has been documented for its production of multiple bioactive...
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Heritability and correlations for honey yield, handling ease, brood quantity, and traits related to resilience in a French honeybee population
There is growing interest in selective breeding of the honeybee, resulting in the emergence of new breeding projects, often with an emphasis on...
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DAP12 interacts with RER1 and is retained in the secretory pathway before assembly with TREM2
DNAX-activating protein of 12 kDa (DAP12) is a transmembrane adapter protein expressed in lymphoid and myeloid lineage cells. It interacts with...
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The autophagy adaptor TRIAD3A promotes tau fibrillation by nested phase separation
Multiple neurodegenerative diseases are characterized by aberrant proteinaceous accumulations of tau. Here, we report a RING-in-between-RING-type E3...
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Zeb1 mediates EMT/plasticity-associated ferroptosis sensitivity in cancer cells by regulating lipogenic enzyme expression and phospholipid composition
Therapy resistance and metastasis, the most fatal steps in cancer, are often triggered by a (partial) activation of the epithelial–mesenchymal...
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Building a translational cancer dependency map for The Cancer Genome Atlas
Cancer dependency maps have accelerated the discovery of tumor vulnerabilities that can be exploited as drug targets when translatable to patients....
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Reduced adipocyte glutaminase activity promotes energy expenditure and metabolic health
Glutamine and glutamate are interconverted by several enzymes and alterations in this metabolic cycle are linked to cardiometabolic traits. Herein,...
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p53 at the crossroads of tumor immunity
The p53 tumor suppressor protein has a plethora of cell-intrinsic functions and consequences that impact diverse cell types and tissues. Recent...
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Long-term biotic homogenization in the East African Rift System over the last 6 million years of hominin evolution
Eastern Africa preserves the most complete record of human evolution anywhere in the world but we have little knowledge of how long-term...
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Fish Iridoviridae: infection, vaccination and immune response
Each year, due to climate change, an increasing number of new pathogens are being discovered and studied, leading to an increase in the number of...
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First Record of Telenomus dilophonotae (Hymenoptera, Scelionidae), Parasitizing Eggs of Erinnyis ello (Lepidoptera, Sphingidae) in Western Paraná, Brazil, with Molecular Characterization and Records of Occurrences
There are few records for Telenomus dilophonotae Cameron, 1913 (Hymenoptera, Scelionidae) from South America. In Brazil, the first occurrence was...
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Exploring the cooperation between nitrogen-fixing and non-fixing alfalfa rhizobia
Alfalfa plays a crucial role in agriculture due to its nitrogen-fixing partnership with rhizobia, resulting in nutritious forage. While the potential...