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A deep learning-driven discovery of berberine derivatives as novel antibacterial against multidrug-resistant Helicobacter pylori
Helicobacter pylori ( H. pylori ) is currently recognized as the primary carcinogenic pathogen associated with gastric tumorigenesis, and its high...
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Chemotherapy’s effects on autophagy in the treatment of Hodgkin’s lymphoma: a sco** review
BackgroundClassical Hodgkin Lymphomas (HL) are a unique malignant growth with an excellent initial prognosis. However, 10–30% of patients will still...
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The role of anti-citrullinated protein antibody in pathogenesis of RA
Rheumatoid arthritis (RA) is a common autoimmune rheumatic disease that causes chronic synovitis, bone erosion, and joint destruction. The...
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Does bilateral Wilms’ tumor involving the collecting system in children have a worse prognosis?
BackgroundThe literature on nephron-sparing surgery (NSS) in children with bilateral Wilms’ tumors (BWT) involving the collection system is mostly...
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Diffuse pulmonary arteriovenous malformation presenting with secondary polycythemia and headaches: a case report
BackgroundPulmonary arteriovenous malformations are a relatively uncommon medical condition, affecting roughly 1 in every 2500 individuals. Of those...
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Machine learning models to predict systemic inflammatory response syndrome after percutaneous nephrolithotomy
ObjectiveThe objective of this study was to develop and evaluate the performance of machine learning models for predicting the possibility of...
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Impact of DAA Treatment for HCV on Hepatocellular Carcinoma in a Predominately African American Population
PurposeThis study tested the hypothesis that our predominately AA medical center population would demonstrate a decline in HCV-driven HCC diagnosis...
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Efficacy and safety of tislelizumab plus bacillus-calmette guérin with or without chemotherapy as a bladder-sparing treatment for high-risk non-muscle-invasive bladder urothelial cancer: a real-world study
BackgroundDespite adequate transurethral resection of the bladder tumor (TURBT) followed by intravesical bacillus-calmette guérin (BCG), high-risk...
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Characteristics of Neonatal Sepsis and Predictive Values of Polyfunctional Assessment of Umbilical Cord Neutrophils Based on Single Cell Proteomic Secretion
The early diagnosis of neonatal sepsis is crucial as it remains a prevalent cause of neonatal mortality. In this study, we conducted an analysis on...
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Surgical outcome of pediatric abdominal trauma at Tertiary Hospital, Northwest Ethiopia, a 3-year retrospective study
IntroductionAbdominal trauma in children is a significant health concern that often leads to severe complications and even death. Children experience...
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The Effect of Obstructive Sleep Apnea on Cognition: A Focus on Decision-Making
Purpose of ReviewIn this review, we discuss the impact of Obstructive Sleep Apnea (OSA), a sleep-related breathing disorder characterized by...
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Analysis of MTHFR C677T genotype and related factors in H-type hypertension in Tibet, China
Background and aimsH-type hypertension is essential hypertension combined with high homocysteine, and both synergistically increase the risk of...
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A Canadian Retrospective Chart Review Evaluating Concomitant Methotrexate De-escalation Patterns in Patients with Rheumatoid Arthritis Treated with Biologic or Targeted Synthetic DMARDs
IntroductionRheumatoid arthritis (RA) guidelines recommend methotrexate (MTX)-anchored therapy with biologic or targeted synthetic disease-modifying...
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Multi-omics differences in the bone marrow between essential thrombocythemia and prefibrotic primary myelofibrosis
Essential thrombocythemia (ET) and prefibrotic primary myelofibrosis (pre-PMF) are Philadelphia chromosome-negative myeloproliferative neoplasms....
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Cardiac effects of direct anti-viral treatment in type II diabetic patients with hepatitis C infection
BackgroundThe link between diabetes mellitus and chronic hepatitis C infection remains well established. It is estimated that up to one third of...
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Isolation and identification of hoylesella marshii causing pleural infection: a case report
BackgroundHoylesella marshii can be isolated from human oral cavities affected by dental pulp and periodontal infections, as well as from the dental...
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An unexpected case of an adnexal hydatid cyst in a pregnant woman: a case report
BackgroundCystic echinococcosis, also known as hydatid disease, is a chronic and endemic illness caused by infection with a parasite called Echinococc...
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Novel genomic variants related to visceral adiposity index (VAI) and body adiposity index (BAI) in Indian sib-pairs
BackgroundObesity is among the leading public health threats globally. Over the last few years, visceral adiposity index (VAI), and body adiposity...
