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Effectiveness of public health spending: Investigating the moderating role of governance using partial least squares structural equation modelling (PLS-SEM)
BackgroundThe link between public health spending (PHS) and population health outcomes (PHO) has been extensively studied. However, in sub-Saharan...
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Bovine colostrum prevents formula-induced gut microbiota dysbiosis in preterm pigs
BackgroundPreterm birth and formula feeding increase the risk of necrotizing enterocolitis (NEC), a gut inflammatory disease known to be associated...
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Evidence-based clinical practice guidelines for the management of acute ankle injuries according to: a PRISMA systematic review and quality appraisal with AGREE II
BackgroundAcute ankle injuries are commonly seen in emergency rooms, with significant social impact and potentially devastating consequences. While...
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Survival, mortality and epidemic risk status of COVID-19: a population-based Study in Golestan province, Iran
BackgroundAppreciating the various dimensions of the coronavirus disease 2019 (COVID-19) pandemic can improve health systems and prepare them to deal...
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Impact of Photobiomodulation on IL1β and TGFβ-1 concentrations in patients with aphthous stomatitis
Laser therapy has shown effectiveness in promoting wound healing by influencing various physiological factors such as blood flow, cytokines,...
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Global burden and cross-country inequalities in stroke and subtypes attributable to diet from 1990 to 2019
Data sourcesThe Global Burden of Diseases, Injuries, and Risk Factors study (GBD) 2019.
BackgroundTo describe burden, and to explore cross-country...
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Health outcomes and healthcare utilization associated with four undiagnosed chronic conditions: evidence from nationally representative survey data in Sri Lanka
BackgroundLow awareness of chronic conditions raises the risk of poorer health outcomes and may result in healthcare utilization and spending in...
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Mining the interpretable prognostic features from pathological image of intrahepatic cholangiocarcinoma using multi-modal deep learning
BackgroundThe advances in deep learning-based pathological image analysis have invoked tremendous insights into cancer prognostication. Still, lack...
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Clinical and genetic analysis of Niemann-Pick disease type C with a novel NPC1 variant
BackgroundNiemann-Pick disease type C poses a significant challenge within the landscape of rare genetic disorders, marked by its connection to...
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A deep learning-driven discovery of berberine derivatives as novel antibacterial against multidrug-resistant Helicobacter pylori
Helicobacter pylori ( H. pylori ) is currently recognized as the primary carcinogenic pathogen associated with gastric tumorigenesis, and its high...
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A randomised controlled trial of Standard Of Care versus RadioAblaTion in Early Stage HepatoCellular Carcinoma (SOCRATES HCC)
BackgroundTherapeutic options for early-stage hepatocellular carcinoma (HCC) in individual patients can be limited by tumor and location, liver...
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Chemotherapy’s effects on autophagy in the treatment of Hodgkin’s lymphoma: a sco** review
BackgroundClassical Hodgkin Lymphomas (HL) are a unique malignant growth with an excellent initial prognosis. However, 10–30% of patients will still...
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The role of anti-citrullinated protein antibody in pathogenesis of RA
Rheumatoid arthritis (RA) is a common autoimmune rheumatic disease that causes chronic synovitis, bone erosion, and joint destruction. The...
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Slowing lung deflation by increasing the expiratory resistance enhances FRC in preterm rabbits
BackgroundAs very preterm infants have surfactant-deficient and highly incompliant lungs, slowing lung deflation during expiration might help...
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Does bilateral Wilms’ tumor involving the collecting system in children have a worse prognosis?
BackgroundThe literature on nephron-sparing surgery (NSS) in children with bilateral Wilms’ tumors (BWT) involving the collection system is mostly...
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General skin and nasal decolonization with octenisan® set before and after elective orthopedic surgery in selected patients at elevated risk for revision surgery and surgical site infections—a single-center, unblinded, superiority, randomized controlled trial (BALGDEC trial)
BackgroundThe preoperative body surface and nasal decolonization may reduce the risk of surgical site infections (SSI) but yields conflicting results...
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Mitochondrial Adaptation in Skeletal Muscle: Impact of Obesity, Caloric Restriction, and Dietary Compounds
Purpose of ReviewThe global obesity epidemic has become a major public health concern, necessitating comprehensive research into its adverse effects...
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Development of the Cutaneous Dermatomyositis Investigator Global Assessment (CDM-IGA): A De Novo IGA of Cutaneous Manifestations of Dermatomyositis
IntroductionDermatomyositis (DM) is a rare systemic autoimmune disease characterized by a distinctive debilitating skin rash and skeletal muscle...
