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Inhibitors of apolipoprotein C3, triglyceride levels, and risk of pancreatitis: a systematic review and meta-analysis
In recent years, novel apoC3 inhibitor therapies for the treatment of hypertriglyceridemia have been developed and assessed through phase II and III...
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Clinical Audit of Obstetric Hysterectomy in a Tertiary Care Centre: An Observational Retroprospective Study
Purpose of StudyThe purpose of this study is to analyse the profile and characteristics of patients who may undergo obstetric hysterectomy, to study...
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Anti-apoptotic Role of Bcl-2-Associated Athanogene-3 Protein Overexpression in the Pathogenesis of Endometrial Cancers: An Aid for New Therapeutic Targets
ObjectiveBcl-2-associated athanogene-3 (BAG-3) is a cytoplasmic multidomain protein member that belongs to the BAG family of co-chaperones that are...
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Sex differences in membrane properties and cellular excitability of dopamine D1 receptor-expressing neurons within the shell of the nucleus accumbens of pre- and mid-adolescent mice
BackgroundThe transition from childhood to adulthood, or adolescence, a developmental stage, is characterized by psychosocial and biological changes....
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The possible short-term of Nigella sativa – L in the management of adolescent polycystic ovarian syndrome: results of a randomized controlled trial
BackgroundPolycystic ovary syndrome (PCOS) is the most common endocrine disorder in reproductive age and the most common cause of infertility due to...
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Influence of prediabetes on the prognosis of patients with myocardial infarction: a meta-analysis
BackgroundPrevious studies evaluating the association between prediabetes the prognosis of patients with acute myocardial infarction (AMI) showed...
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Enrichment of cell cycle pathways in progesterone-treated endometrial organoids of infertile women compared to fertile women
PurposeTo investigate whether the transcriptome profile differs between progesterone-treated infertile and fertile endometrial organoids.
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The relationship between dietary habits and menstruation problems in women: a cross-sectional study
BackgroundNutrition is important to the management and relief of the symptoms in menstrual disorders. This study aims to investigate the relationship...
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Basal FSH values are positively associated with aneuploidy incidence in pre-advanced maternal age (AMA) but not in AMA patients
PurposeTo assess the impact of maternal age on the association between maternal basal FSH and aneuploidy.
MethodsA retrospective study including...
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Does metformin really reduce prostate cancer risk: an up-to-date comprehensive genome-wide analysis
BackgroundThe relationship between metformin use and prostate cancer (PCa) risk has yet to be clear despite more than a decade of debate on this...
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A DPC Database Study on the Safety of Atezolizumab/Carboplatin/Etoposide in Extensive-Disease Small Cell Lung Cancer in Japanese Patients
IntroductionAtezolizumab, carboplatin, and etoposide (ACE) therapy is a standard of care for extensive-disease small cell lung cancer (SCLC);...
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Improvement of early miscarriage rates in women with adenomyosis via oxytocin receptor antagonist during frozen embryo transfer-a propensity score-matched study
BackgroundDysfunctional uterine peristalsis seems to play a pivotal role in hindering embryo implantation among women diagnosed with adenomyosis....
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FOK1 and APA1 Gene Polymorphism Among Polycystic Ovary Syndrome: A Prospective Cohort Study
BackgroundVitamin D receptor (VDR) regulates insulin sensitivity, lipid metabolism and hormone balance in women. There are contrasting opinions on...
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Changes in maternity care policies and practices that support breastfeeding as measured by the Ten Steps to Successful Breastfeeding — United States, 2018–2022
BackgroundExperiences during the birth hospitalization affect a family’s ability to establish and maintain breastfeeding. The Ten Steps to Successful...
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Safety of embryo cryopreservation: insights from mid-term placental transcriptional changes
BackgroundIn recent years, with benefits from the continuous improvement of clinical technology and the advantage of fertility preservation, the...
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The impact of Paclitaxel-based hyperthermic intraperitoneal chemotherapy in advanced high-grade serous ovarian cancer patients - interim analysis of safety and immediate efficacy of a randomized control trial (C-HOC trial)
ObjectiveThis study evaluates the potential superiority of combining paclitaxel-based hyperthermic intraperitoneal chemotherapy (HIPEC) with...
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Promoting men-inclusive maternity services: exploring the expectations, experiences and needs of men as fathers
AimThis study aimed to explore the ‘real time’ expectations, experiences and needs of men who attend maternity services to inform the development of...
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Reliability and Validation of the PFIQ-7 and PFDI-20 in the Luganda Language
Introduction and HypothesisPelvic floor disorders (PFDs) impact women worldwide and are assessed using instruments such as the Pelvic Floor Distress...