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Diabetic myonecrosis complicated by emphysematous pyomyositis and abscess caused by Escherichia coli: a case report
BackgroundNecrotizing myopathies and muscle necrosis can be caused by immune-mediated mechanisms, drugs, ischemia, and infections, and differential...
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Biologics or Janus Kinase Inhibitors in Rheumatoid Arthritis Patients Who are Insufficient Responders to Conventional Anti-Rheumatic Drugs
Rheumatoid arthritis (RA) is a chronic immune-mediated inflammatory disease which can induce progressive disability if not properly treated early....
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Diagnostic performance of CT/MRI LI-RADS v2018 in non-cirrhotic steatotic liver disease
ObjectiveTo assess the performance of computed tomography (CT)/magnetic resonance imaging (MRI) Liver Imaging Reporting and Data System (LI-RADS)...
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Harnessing the potential of hydrogels for advanced therapeutic applications: current achievements and future directions
The applications of hydrogels have expanded significantly due to their versatile, highly tunable properties and breakthroughs in biomaterial...
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Antibody–Drug Conjugates in the Pipeline for Treatment of Melanoma: Target and Pharmacokinetic Considerations
Melanoma is an aggressive, rapidly develo** form of skin cancer that affects about 22 per 100,000 individuals. Treatment options for melanoma...
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Pulmonary embolism in patients with chronic coronary syndrome masquerading as acute coronary syndrome: a case report and literature review
BackgroundPulmonary embolisms (PEs) exhibit clinical features similar to those of acute coronary syndrome (ACS), including electrocardiographic...
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Classification of the oesophageal perforation
ObjectivesEsophageal perforations are a complex clinical scenario that have been poorly studied. To date, there is no grading of esophageal...
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Psychological Distress in the Era of Psychological Safety
There has been a growing disconnect between learners and educators within medical education. As the landscape of medical education has been altered...
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The role of histamine and its receptors in breast cancer: from pathology to therapeutic targets
Breast cancer is the most common malignancy in women, and despite the development of new treatment methods and the decreasing mortality rate in...
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New device for assessment of endothelial function: plethysmographic flow-mediated vasodilation (pFMD)
Measurement of flow-mediated vasodilation (FMD) in the brachial artery by using ultrasound is a well-established technique for evaluating endothelial...
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7 T and beyond: toward a synergy between fMRI-based presurgical map** at ultrahigh magnetic fields, AI, and robotic neurosurgery
Presurgical evaluation with functional magnetic resonance imaging (fMRI) can reduce postsurgical morbidity. Here, we discuss presurgical fMRI...
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Postoperative hyperglycemia among adult non-diabetic surgical patients at University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia
BackgroundPostoperative hyperglycemia is associated with morbidity and mortality in non-diabetic surgical patients. However, there is limited...
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A Randomized, Open-Label, Phase I, Single-Dose Study of Antisense Oligonucleotide, Vupanorsen, in Chinese Adults with Elevated Triglycerides
BackgroundVupanorsen is a GalNAc 3 -conjugated antisense oligonucleotide targeting angiopoietin-like 3 (ANGPTL3) mRNA shown to reduce atherogenic...