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Fish Iridoviridae: infection, vaccination and immune response
Each year, due to climate change, an increasing number of new pathogens are being discovered and studied, leading to an increase in the number of...
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Die Deutsche Gesellschaft für Rheumatologie und Klinische Immunologie e. V. (DGRh) und die COVID-19-Pandemie
The pandemic led to a global disruption of public life unprecedented in modern times due to an infectious disease, which certainly caused additional...
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Multimodal training protocols on unstable rather than stable surfaces better improve dynamic balance ability in older adults
BackgroundThere has been growing interest in using unstable devices in training protocols. This study aimed to assess the effectiveness of two...
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CAR-NKT Cells in Asthma: Use of NKT as a Promising Cell for CAR Therapy
NKT cells, unique lymphocytes bridging innate and adaptive immunity, offer significant potential for managing inflammatory disorders like asthma....
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Patientenbefragung zum Einsatz von Videosprechstunden in der ambulanten Behandlung von chronischem Pruritus
BackgroundAnalyses of patient evaluations and barriers to the implementation of teledermatology procedures are still rare. The aim of this study was...
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Neues in der Diagnostik und Therapie der aktinischen Keratose
Actinic keratosis (AK) is among the most common conditions in dermatology in an increasingly aging population. However, the presence of severe field...
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Budesonide in Liver Immunology: A Therapeutic Opportunity in Liver Transplantation
Purpose of ReviewA major remaining challenge in liver transplantation is achieving the balance between adequate immunosuppression to prevent...
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Welches Potential hat ChatGPT 3.5 für eine qualifizierte Patienteninformation?
IntroductionThe chatbot ChatGPT represents a milestone in the interaction between humans and large databases that are accessible via the internet. It...
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Cross-species transmission and histopathological variation in specific-pathogen-free minipigs infected with different hepatitis E virus strains
Hepatitis E virus (HEV) is a major cause of viral hepatitis worldwide. Pigs are the natural host of HEV genotype 3 and the main reservoir of HEV. As...
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Exploring the complex associations among risks of malnutrition, sarcopenia, and frailty in community-dwelling older adults
BackgroundMalnutrition, sarcopenia, and frailty are age-related conditions that are associated with multiple health-related negative outcomes....
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Emerging Logistic Challenges, Health Disparities, and Bioethical Concerns in Kidney Xenotransplantation: A Literature Review
Purpose of ReviewXenotransplantation has emerged as a promising frontier in the field of kidney transplant surgery as a result of recent successful...
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Long-term survivals of immune checkpoint inhibitors as neoadjuvant and adjuvant therapy in dMMR/MSI-H colorectal and gastric cancers
BackgroundThe long-term survival benefit of immune checkpoint inhibitors (ICIs) in neoadjuvant and adjuvant settings is unclear for colorectal...
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Gut-Derived Short-Chain Fatty Acids and Macrophage Modulation: Exploring Therapeutic Potentials in Pulmonary Fungal Infections
Short-chain fatty acids (SCFAs), such as acetate, propionate, and butyrate, modulate immune cell functions, particularly macrophages. This review...
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In vitro T cell responses to PD-1 blockade are reduced by IFN-α but do not predict therapy response in melanoma patients
PD-1 blockade therapy has revolutionized melanoma treatment, but still not all patients benefit and pre-treatment identification of those patients is...
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Efficacy of adjuvant immune checkpoint inhibitors pembrolizumab or nivolumab in melanoma patients ≥ 75 years: results of a real-world cohort including 456 patients
BackgroundImmune checkpoint inhibitors (ICI) applied in patients with melanoma in an adjuvant setting have proven safety and efficacy in several...
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Salmonella enteritidis acquires phage resistance through a point mutation in rfbD but loses some of its environmental adaptability
Phage therapy holds promise as an alternative to antibiotics for combating multidrug-resistant bacteria. However, host bacteria can quickly produce...