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Emerging biologic augmentation strategies for meniscal repair: a systematic review
BackgroundMeniscal repair should be the gold standard. However, the meniscus is poorly vascularized and even an excellent meniscus repair may not...
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Effectiveness of synthetic versus autologous bone grafts in foot and ankle surgery: a systematic review and meta-analysis
BackgroundAll orthopaedic procedures, comprising foot and ankle surgeries, seemed to show a positive trend, recently. Bone grafts are commonly...
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Diffusion-tensor magnetic resonance imaging as a non-invasive assessment of extracellular matrix remodeling in lumbar paravertebral muscles of rats with sarcopenia
BackgroundExtracellular matrix (ECM) remodeling in skeletal muscle is a significant factor in the development of sarcopenia. This study aims to...
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Anti-α-1,4-D-polygalacturonic acid antibodies as a new biomarker for juvenile idiopathic arthritis
ObjectiveDiagnosing juvenile idiopathic arthritis (JIA) is challenging. Our study aimed to investigate the clinical significance of...
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Prioritizing drug targets in systemic lupus erythematosus from a genetic perspective: a druggable genome-wide Mendelian randomization study
ObjectivesSystemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease with an unsatisfactory state of treatment. We aim to explore novel...
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Non-osteoporotic fractures are associated with increased risk of subsequent major osteoporotic fractures
SummaryWe studied the association between non-osteoporotic fractures and future major osteoporotic fractures, using UK health records....
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The effect of radiation synovectomy with phosphorus-32 on the pain and swelling in 31 RA patients with resistant monoarthritis of the knee
IntroductionRheumatoid arthritis (RA) is a chronic inflammatory disease characterized by symmetric polyarthritis. RA is routinely treated by various...
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Changes in femoral anteversion after intramedullary nailing for pediatric femoral shaft fracture: a multicenter study
BackgroundThe rotational change after using a flexible intramedullary (IM) nail for femoral shaft fractures has been a concern for many surgeons....
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A DPC Database Study on the Safety of Atezolizumab/Carboplatin/Etoposide in Extensive-Disease Small Cell Lung Cancer in Japanese Patients
IntroductionAtezolizumab, carboplatin, and etoposide (ACE) therapy is a standard of care for extensive-disease small cell lung cancer (SCLC);...
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Serum GM-CSF level is a predictor of treatment response to tocilizumab in rheumatoid arthritis patients: a prospective observational cohort study
BackgroundThe aim of this prospective observational cohort study was to unveil the predictors of treatment response to tocilizumab (TCZ) therapy in...
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People with osteoarthritis have a higher component of neuropathic pain as compared to those with rheumatoid arthritis: A cross-sectional study
Neuropathic pain may be present in a proportion of patients with osteoarthritis (OA) and rheumatoid arthritis (RA). Its presence may lead to the...
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Preliminarily exploring the intraoperative ultrasonography characteristics of patients with degenerative cervical myelopathy
BackgroundHow to quickly read and interpret intraoperative ultrasound (IOUS) images of patients with degenerative cervical myelopathy (DCM) to obtain...
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Exosomes derived from human urine–derived stem cells ameliorate IL-1β-induced intervertebral disk degeneration
BackgroundHuman intervertebral disk degeneration (IVDD) is a sophisticated degenerative pathological process. A key cause of IVDD progression is...
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Correlation between neuropsychiatric systemic lupus erythematosus and immunological markers: a real-world retrospective study
ObjectivesThis study aimed to investigate disparities in clinical profiles and autoantibody patterns between patients with and without...
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Emotional intelligence: a novel predictor of quality of life in patients with systemic sclerosis
Systemic sclerosis (SSc), a chronic systemic autoimmune disease, affects skin and internal organs compromising organ function and leading to...
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The dual amylin and calcitonin receptor agonist KBP-336 elicits a unique combination of weight loss, antinociception and bone protection – a novel disease-modifying osteoarthritis drug
BackgroundDespite the extensive research to provide a disease-modifying osteoarthritis drug (DMOAD), there is still no approved DMOAD. Dual amylin...
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Blood pressure is associated with knee pain severity in middle-aged and elderly individuals with or at risks for osteoarthritis: data from the Osteoarthritis Initiative
BackgroundHypertension is a common comorbidity of osteoarthritis (OA). Joint pain is the main clinical manifestation of OA. Knowledge about the...
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The relationship between the duration and the retraction and atrophy grades in traumatic isolated full-thickness supraspinatus tears in young patients
BackgroundThe study aimed to determine the grade of retraction and atrophy according to the time elapsed in traumatic isolated full-thickness...
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Biomechanical evaluation of different medial column fixation patterns for valgus pilon fractures
BackgroundThe purpose of this study was to perform a biomechanical analysis to compare different medial column fixation patterns for valgus pilon...
