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In vitro and in vivo dissolution of biocompatible S59 glass scaffolds
Fabrication of porous tissue-engineering scaffolds from bioactive glasses (BAG) is complicated by the tendency of BAG compositions to crystallize in...
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Extracellular vesicle miRNAs for predicting the efficacy of late-line treatment with anlotinib in patients with lung adenocarcinoma
BackgroundAnlotinib is a targeted therapy indicated for some malignancies, including advanced non-small cell lung cancer (NSCLC). However,...
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Intraocular pressure control efficacy and safety of HA-Mg glaucoma drainage plate implantation in the anterior chamber of rabbit eyes
AbstractThe current clinical application of glaucoma drainage devices is made of non-degradable materials. These non-degradable drainage devices...
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Biocompatible PLGA-PCL nanobeads for efficient delivery of curcumin to lung cancer
Lung cancer has been mentioned as the first and second most prevalent cancer among males and females worldwide, respectively since conventional...
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Quantitatively measuring the cytotoxicity of viscous hydrogels with direct cell sampling in a micro scale format “MicroDrop” and its comparison to CCK8
Tissue engineering holds promise for develo** therapeutic applications using viscous materials e.g. hydrogels. However, assessing the cytotoxicity...
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Titanium-doped phosphate glasses containing zinc and strontium applied in bone regeneration
Phosphate bioactive glass has been studied for its advanced biodegradability and active ion release capability. Our previous research found that...
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In vitro cytocompatibility of triclosan coated Polyglactin910 sutures
Bioabsorbable sutures can improve the medical functions of existing non-absorbable sutures, and may produce new medical effects, and are expected to...
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Biological and mechanical performance of calcium phosphate cements modified with phytic acid
Calcium phosphate cements, primarily brushite cements, require the addition of setting retarders to ensure adequate processing time and...
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Theranostic nanoparticles ZIF-8@ICG for pH/NIR-responsive drug-release and NIR-guided chemo-phototherapy against non-small-cell lung cancer
This study leverages nanotechnology by encapsulating indocyanine green (ICG) and paclitaxel (Tax) using zeolitic imidazolate frameworks-8 (ZIF-8) as...
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Optimizing alkaline hydrothermal treatment for biomimetic smart metallic orthopedic and dental implants
Orthopedic and dental implant failure continues to be a significant concern due to localized bacterial infections. Previous studies have attempted to...
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3D Spongin-Based Scaffolds from Marine Demosponge Haliclona sp. for Biomedical Engineering Approaches Based on Mesenchymal Stem Cells
BackgroundSpongin is a versatile organic protein derived from marine sponges, similar to collagen. It has high elasticity after hydration and is used...
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Biocompatibility of nano/micro-sized pyrophyllite particles by pulmo, liver, kidney and gastric mucosis cells
Pyrophyllite is the least studied natural clay in terms of its potential in biomedical applications, although there are many deposits of this...
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Investigating layer-by-layer chitosan-dextran sulfate-coated mesoporous silica as a pH-sensitive drug delivery system
Mesoporous silica nanoparticles (MSNPs) coated by chitosan (CS) were shown to be a proper candidate as a carrier for drug delivery purposes. However,...
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Delivery of letrozole-encapsulated niosomes via a 3D bioprinting gelatin–alginate scaffold for potential breast cancer treatment
3D printing technology is a powerful tool in scaffold engineering for biomedical applications, especially in anticancer activities and drug delivery....
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A novel PH1/pE27HGFK1 nanoparticles for orthotopic glioblastoma therapy
BackgroundThe therapeutic resistance to ionizing radiation (IR) and angiogenesis inhibitors is a great challenge for clinicians in the treatment of...
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Direct profiling of breast cancer-derived extracellular vesicles using Pd-perovskite electrochemical biosensing platform
Extracellular vesicles (EVs) harbor several signaling molecules to maintain intercellular communication. Based on the exosomal cargo type, metabolic,...
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An intelligent and self-assembled nanoscale metal organic framework (99mTC-DOX loaded Fe3O4@FeIII-tannic acid) for tumor targeted chemo/chemodynamic theranostics
BackgroundRecent advances in clinical transformation research have focused on chemodynamic theranostics as an emerging strategy for tackling cancer....
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Black TiO2-based nanoparticles as Toll-like receptor stimulator delivery system for enhanced photothermal-immunotherapy of pancreatic cancer
BackgroundThe tumor-specific immune responses, essential for removing residual lesions and preventing tumor metastases, can be stimulated by...
