Search
Search Results
-
The autophagy adaptor TRIAD3A promotes tau fibrillation by nested phase separation
Multiple neurodegenerative diseases are characterized by aberrant proteinaceous accumulations of tau. Here, we report a RING-in-between-RING-type E3...
-
Zeb1 mediates EMT/plasticity-associated ferroptosis sensitivity in cancer cells by regulating lipogenic enzyme expression and phospholipid composition
Therapy resistance and metastasis, the most fatal steps in cancer, are often triggered by a (partial) activation of the epithelial–mesenchymal...
-
Exploring the cooperation between nitrogen-fixing and non-fixing alfalfa rhizobia
Alfalfa plays a crucial role in agriculture due to its nitrogen-fixing partnership with rhizobia, resulting in nutritious forage. While the potential...
-
Diagnostic applicability of mitogenomics in uncovering intraspecific carangid diversifications: insights into phylogeny, divergence time, and characterization of two cryptic Selaroides leptolepis mitogenomes
Carangidae is an economically important fish family comprised of 32 genera with more than 140 circumglobally distributed species. Its members exhibit...
-
Naturalized alien flora of Uzbekistan: species richness, origin and habitats
This is the first study providing an up-to-date account of the alien flora in Uzbekistan and analyzing the relationship between the invasion status...
-
-
-
Restructuring of Skull Modularity Pattern in Evolution Within Myotis myotis–Myotis blythii Species Group (Vespertilionidae, Chiroptera, Mammalia)
Studies of differences in modularity and integration among the related species can provide important information on their evolution. We argue that...
-
(Re)Emerging disease and conflict risk in Africa, 1997–2019
While the number of infectious zoonotic disease outbreaks has been rising, their impact on civil war and social conflict is poorly understood. This...
-
Changes in benthic communities in Blagopoluchiya Bay (Novaya Zemlya, Kara Sea): the influence of the snow crab
Until recently, the Kara Sea was a stable ecosystem unaffected by alien species invasions. However, at the beginning of the twenty-first century, the...
-
Aberrant telomeric structures and serum markers of telomere dysfunction in healthy aging: a preliminary study
Telomeres undergo a progressive shortening process as individuals age, and it has been proposed that severely shortened and dysfunctional telomeres...
-
The influence of sex-specific factors on biological transformations and health outcomes in aging processes
The aging process demonstrates notable differences between males and females, which are key factors in disease susceptibility and lifespan. The...
-
Red-rumped agouti (Dasyprocta leporina linnaeus, 1758) yolk sac development during the early gestation stage
Phylogenetically, the yolk sac is an ancient structure in vertebrate evolution and crucial in the placentation of viviparous animals, playing an...
-
Progress and perspectives of metabolic biomarkers in human aortic dissection
BackgroundAortic dissection (AD) significantly threated human cardiovascular health, extensive clinical-scientific research programs have been...
-
Pressure sensing of lysosomes enables control of TFEB responses in macrophages
Polymers are endocytosed and hydrolysed by lysosomal enzymes to generate transportable solutes. While the transport of diverse organic solutes across...
-
Full-length GSDME mediates pyroptosis independent from cleavage
Gasdermin (GSDM) family proteins, known as the executors of pyroptosis, undergo protease-mediated cleavage before inducing pyroptosis. We here...
-
Neutrophil-derived migrasomes are an essential part of the coagulation system
Migrasomes are organelles that are generated by migrating cells. Here we report the key role of neutrophil-derived migrasomes in haemostasis. We...
-
The neural network RTNet exhibits the signatures of human perceptual decision-making
Convolutional neural networks show promise as models of biological vision. However, their decision behaviour, including the facts that they are...
-
Vaginal irritation testing—prospects of human organotypic vaginal tissue culture models
Personal lubricants intended for local or systemic delivery via the vaginal route can induce vaginal irritation, damage the vaginal epithelial...