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Naturalized alien flora of Uzbekistan: species richness, origin and habitats
This is the first study providing an up-to-date account of the alien flora in Uzbekistan and analyzing the relationship between the invasion status...
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The autophagy adaptor TRIAD3A promotes tau fibrillation by nested phase separation
Multiple neurodegenerative diseases are characterized by aberrant proteinaceous accumulations of tau. Here, we report a RING-in-between-RING-type E3...
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Zeb1 mediates EMT/plasticity-associated ferroptosis sensitivity in cancer cells by regulating lipogenic enzyme expression and phospholipid composition
Therapy resistance and metastasis, the most fatal steps in cancer, are often triggered by a (partial) activation of the epithelial–mesenchymal...
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Exploring the cooperation between nitrogen-fixing and non-fixing alfalfa rhizobia
Alfalfa plays a crucial role in agriculture due to its nitrogen-fixing partnership with rhizobia, resulting in nutritious forage. While the potential...
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Diagnostic applicability of mitogenomics in uncovering intraspecific carangid diversifications: insights into phylogeny, divergence time, and characterization of two cryptic Selaroides leptolepis mitogenomes
Carangidae is an economically important fish family comprised of 32 genera with more than 140 circumglobally distributed species. Its members exhibit...
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Restructuring of Skull Modularity Pattern in Evolution Within Myotis myotis–Myotis blythii Species Group (Vespertilionidae, Chiroptera, Mammalia)
Studies of differences in modularity and integration among the related species can provide important information on their evolution. We argue that...
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Changes in benthic communities in Blagopoluchiya Bay (Novaya Zemlya, Kara Sea): the influence of the snow crab
Until recently, the Kara Sea was a stable ecosystem unaffected by alien species invasions. However, at the beginning of the twenty-first century, the...
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Aberrant telomeric structures and serum markers of telomere dysfunction in healthy aging: a preliminary study
Telomeres undergo a progressive shortening process as individuals age, and it has been proposed that severely shortened and dysfunctional telomeres...
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The influence of sex-specific factors on biological transformations and health outcomes in aging processes
The aging process demonstrates notable differences between males and females, which are key factors in disease susceptibility and lifespan. The...
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Red-rumped agouti (Dasyprocta leporina linnaeus, 1758) yolk sac development during the early gestation stage
Phylogenetically, the yolk sac is an ancient structure in vertebrate evolution and crucial in the placentation of viviparous animals, playing an...
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Progress and perspectives of metabolic biomarkers in human aortic dissection
BackgroundAortic dissection (AD) significantly threated human cardiovascular health, extensive clinical-scientific research programs have been...
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Pressure sensing of lysosomes enables control of TFEB responses in macrophages
Polymers are endocytosed and hydrolysed by lysosomal enzymes to generate transportable solutes. While the transport of diverse organic solutes across...
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Full-length GSDME mediates pyroptosis independent from cleavage
Gasdermin (GSDM) family proteins, known as the executors of pyroptosis, undergo protease-mediated cleavage before inducing pyroptosis. We here...
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Neutrophil-derived migrasomes are an essential part of the coagulation system
Migrasomes are organelles that are generated by migrating cells. Here we report the key role of neutrophil-derived migrasomes in haemostasis. We...
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Vaginal irritation testing—prospects of human organotypic vaginal tissue culture models
Personal lubricants intended for local or systemic delivery via the vaginal route can induce vaginal irritation, damage the vaginal epithelial...
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The Goldilocks Dilemma: the optimal management strategy for invasive trees in the Atlantic Forest
This study addresses the broader issue of invasive species management, particularly within the context of highly biodiverse yet threatened ecosystems...
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Exploring the osteogenic potential of semisynthetic triterpenes from Combretum leprosum: An in vitro and in silico study
Combretum leprosum Mart. is a plant of the Combretaceae family, widely distributed in the Northeast region of Brazil, popularly used as an...
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Fractal morphology of mechanosensory lateral-line canals in Stichaeidae
The marine teleost family Stichaeidae shows considerable variation in the morphology of mechanosensory lateral-line canals across its six...
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RNA scaffolds the Golgi ribbon by forming condensates with GM130
The mammalian Golgi is composed of stacks that are laterally connected into a continuous ribbon-like structure. The integrity and function of the...
