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Optimization of biotransformation processes of Camarosporium laburnicola to improve production yields of potent telomerase activators
BackgroundTelomerase activators are promising agents for the healthy aging process and the treatment/prevention of short telomere-related and...
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Map** a sustainable approach: biosynthesis of lactobacilli-silver nanocomposites using whey-based medium for antimicrobial and bioactivity applications
This study explores a sustainable approach for synthesizing silver nanocomposites (AgNCs) with enhanced antimicrobial and bioactivity using safe Lactobacillus...
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Production of succinate with two CO2 fixation reactions from fatty acids in Cupriavidus necator H16
BackgroundBiotransformation of CO 2 into high-value-added carbon-based products is a promising process for reducing greenhouse gas emissions. To...
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Construction of lignan glycosides biosynthetic network in Escherichia coli using mutltienzyme modules
BackgroundDue to the complexity of the metabolic pathway network of active ingredients, precise targeted synthesis of any active ingredient on a...
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Optimization, gene cloning, expression, and molecular docking insights for enhanced cellulase enzyme production by Bacillus amyloliquefaciens strain elh1
BackgroundIn this study, we isolated a cellulase-producing bacterium, Bacillus amyloliquefaciens strain elh, from rice peel. We employed two...
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Natural dyes developed by microbial-nanosilver to produce antimicrobial and anticancer textiles
Develo** special textiles (for patients in hospitals for example) properties, special antimicrobial and anticancer, was the main objective of the...
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Streamlining heterologous expression of top carbonic anhydrases in Escherichia coli: bioinformatic and experimental approaches
BackgroundCarbonic anhydrase (CA) enzymes facilitate the reversible hydration of CO 2 to bicarbonate ions and protons. Identifying efficient and...
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Interplay between photosynthetic electron flux and organic carbon sinks in sucrose-excreting Synechocystis sp. PCC 6803 revealed by omics approaches
BackgroundAdvancing the engineering of photosynthesis-based prokaryotic cell factories is important for sustainable chemical production and requires...
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A review on microbes mediated resource recovery and bioplastic (polyhydroxyalkanoates) production from wastewater
BackgroundPlastic is widely utilized in packaging, frameworks, and as coverings material. Its overconsumption and slow degradation, pose threats to...
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Rational construction of a high-quality and high-efficiency biosynthetic system and fermentation optimization for A82846B based on combinatorial strategies in Amycolatopsis orientalis
BackgroundOritavancin is a new generation of semi-synthetic glycopeptide antibiotics against Gram-positive bacteria, which served as the first and...
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Engineering strategies for enhanced 1′, 4′-trans-ABA diol production by Botrytis cinerea
BackgroundCurrently, industrial fermentation of Botrytis cinerea is a significant source of abscisic acid (ABA). The crucial role of ABA in plants...
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‘Small volume—big problem’: culturing Yarrowia lipolytica in high-throughput micro-formats
With the current progress in the ‘design’ and ‘build’ stages of the ‘design-build-test-learn’ cycle, many synthetic biology projects become...
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Metabolic engineering of Saccharomyces cerevisiae for chelerythrine biosynthesis
BackgroundChelerythrine is an important alkaloid used in agriculture and medicine. However, its structural complexity and low abundance in nature...
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Efficient production of guanosine in Escherichia coli by combinatorial metabolic engineering
BackgroundGuanosine is a purine nucleoside that is widely used as a raw material for food additives and pharmaceutical products. Microbial...
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Cytokinetic engineering enhances the secretory production of recombinant human lysozyme in Komagataella phaffii
BackgroundHuman lysozyme (hLYZ) is a natural antibacterial protein with broad applications in food and pharmaceutical industries. Recombinant...
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Volatile communication in Actinobacteria: a language for secondary metabolism regulation
BackgroundVolatile compounds are key elements in the interaction and communication between organisms at both interspecific and intraspecific levels....
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Comprehensive network of stress-induced responses in Zymomonas mobilis during bioethanol production: from physiological and molecular responses to the effects of system metabolic engineering
Nowadays, biofuels, especially bioethanol, are becoming increasingly popular as an alternative to fossil fuels. Zymomonas mobilis is a desirable...
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Bi-directionalized promoter systems allow methanol-free production of hard-to-express peroxygenases with Komagataella Phaffii
BackgroundHeme-incorporating peroxygenases are responsible for electron transport in a multitude of organisms. Yet their application in biocatalysis...
