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  1. No Access

    Article

    Patterns and conformations of commonly occurring supersecondary structures (basic motifs) in protein data bank

    Short peptides connectingα-helices andβ-strands have been analyzed in 240 proteins refined at resolutions of 0.25 nm or better. Connecting peptides of lengths between one and five residues have been classified as...

    Zhirong Sun, Bo Jiang in Journal of Protein Chemistry (1996)

  2. No Access

    Article

    The evolution simulation of zinc finger domain sequence

    Zhirong Sun, Hao Han in Chinese Science Bulletin (1997)

  3. No Access

    Article

    Applying genetic algorithms to the study of protein mutation theory

    Genetic algorithms were applied to the study of simulation of protein mutation carried out on two-dimensional lattice model; to the study of effects of single mutation and double mutation on protein folding an...

    Zhirong Sun, Hao Han, Wang in Chinese Science Bulletin (1998)

  4. No Access

    Article

    Protein Structure Prediction in a 210-Type Lattice Model: Parameter Optimization in the Genetic Algorithm Using Orthogonal Array

    We have applied the orthogonal array method to optimize the parameters in the genetic algorithm of the protein folding problem. Our study employed a 210-type lattice model to describe proteins, where the orientat...

    Zhirong Sun, **aofeng **a, Qing Guo, Dong Xu in Journal of Protein Chemistry (1999)

  5. No Access

    Article

    A new method of research on molecular evolution of proteinase superfamily

    The molecular evolutionary tree, also known as a phylogenetic tree, of the serine proteinase superfamily was constructed by means of structural alignment. Three-dimensional structures of proteins were aligned ...

    Zhirong Sun, **nglai Ji, Shengmin Hu, Yu Wang, Fuchu He in Chinese Science Bulletin (2001)

  6. Article

    Bioinformatical study on the proteomics and evolution of SARS-CoV

    A novel coronavirus has been identified as the causative agent of the severe acute respiratory syndrome (SARS). For all the SARS-CoV associated proteins derivated from the SARS-CoV genome, the physiochemical p...

    Shuqun Liu, Tao Guo, **nglai Ji, Zhirong Sun in Chinese Science Bulletin (2003)

  7. No Access

    Article

    Structural and functional characterization of the human CCR5 receptor in complex with HIV gp120 envelope glycoprotein and CD4 receptor by molecular modeling studies

    The entry of human immunodeficiency virus (HIV) into cells depends on a sequential interaction of the gp120 envelope glycoprotein with the cellular receptors CD4 and members of the chemokine receptor family. T...

    Shuqun Liu, Shixiu Fan, Zhirong Sun in Journal of Molecular Modeling (2003)

  8. Article

    Open Access

    NBA-Palm: prediction of palmitoylation site implemented in Naïve Bayes algorithm

    Protein palmitoylation, an essential and reversible post-translational modification (PTM), has been implicated in cellular dynamics and plasticity. Although numerous experimental studies have been performed to...

    Yu Xue, Hu Chen, Changjiang **, Zhirong Sun, Xuebiao Yao in BMC Bioinformatics (2006)

  9. No Access

    Article

    GO molecular function coding based protein subcellular localization prediction

    Subcellular localization is an important feature of proteins which is closely correlated to their function. In this work, we tried to develop a new coding method of using those location predictive molecular fu...

    **Cheng Shen, Zhang Song, ZhiRong Sun in Chinese Science Bulletin (2007)

  10. Article

    Open Access

    DBMLoc: a Database of proteins with multiple subcellular localizations

    Subcellular localization information is one of the key features to protein function research. Locating to a specific subcellular compartment is essential for a protein to function efficiently. Proteins which h...

    Song Zhang, Xuefeng **a, **cheng Shen, Yun Zhou, Zhirong Sun in BMC Bioinformatics (2008)

  11. Article

    Open Access

    Molecular evolution of Cide family proteins: Novel domain formation in early vertebrates and the subsequent divergence

    Cide family proteins including Cidea, Cideb and Cidec/Fsp27, contain an N-terminal CIDE-N domain that shares sequence similarity to the N-terminal CAD domain (NCD) of DNA fragmentation factors Dffa/Dff45/ICAD ...

    Congyang Wu, Yinxin Zhang, Zhirong Sun, Peng Li in BMC Evolutionary Biology (2008)

  12. Article

    Open Access

    Inferring protein function by domain context similarities in protein-protein interaction networks

    Genome sequencing projects generate massive amounts of sequence data but there are still many proteins whose functions remain unknown. The availability of large scale protein-protein interaction data sets make...

    Song Zhang, Hu Chen, Ke Liu, Zhirong Sun in BMC Bioinformatics (2009)

  13. Article

    Witness the prosperity: 25 years of life science revival in Tsinghua University

    Zhirong Sun in Protein & Cell (2010)

  14. No Access

    Article

    Identifying changed protein-protein interactions in biological processes by gene coexpression analysis

    The interaction strength between 2 proteins is not constant but variable under different conditions. For a given biological process, identification of protein-protein interactions (PPIs) undergoing dynamic cha...

    Ting Zhang, XueGong Zhang, ZhiRong Sun in Chinese Science Bulletin (2010)

  15. No Access

    Article

    Preparation and characterization of Pd/PPy-SDS/foam-Ni and Pd/PPy-CTAB/foam-Ni electrodes with high electroactive surface area

    Surfactant-doped electrodes, palladium/polymeric pyrrole-sodium dodecyl sulfate/foam-nickel (Pd/PPy-SDS/foam-Ni) electrode and palladium/polymeric pyrrole-cetyl trimethyl ammonium bromide/foam-nickel (Pd/PPy-C...

    Zhirong Sun, Lin Ma, **ang Hu in Journal of Solid State Electrochemistry (2011)

  16. Article

    Open Access

    Cancer core modules identification through genomic and transcriptomic changes correlation detection at network level

    Identification of driver mutations among numerous genomic alternations remains a critical challenge to the elucidation of the underlying mechanisms of cancer. Because driver mutations by definition are associa...

    Wenting Li, Rui Wang, Linfu Bai, Zhangming Yan, Zhirong Sun in BMC Systems Biology (2012)

  17. No Access

    Article

    Propofol Protects Against Angiotensin II-Induced Mouse Hippocampal HT22 Cells Apoptosis Via Inhibition of p66Shc Mitochondrial Translocation

    Hippocampal neuronal oxidative stress and apoptosis have been reported to be involved in cognitive impairment, and angiotensin II could induce hippocampal oxidative stress and apoptosis. Propofol is a widely ...

    Minmin Zhu, Jiawei Chen, Meilin Wen, Zhirong Sun, **a Sun in NeuroMolecular Medicine (2014)

  18. No Access

    Article

    Dechlorination of pentachlorophenol (PCP) in aqueous solution on novel Pd-loaded electrode modified with PPy–SDBS composite film

    Pentachlorophenol (PCP) is a persistent pollutant and a suspected human carcinogen. It can be found in the air, water, and soil and enters the environment through evaporation from treated wood surfaces, indust...

    Zhirong Sun, Xuefeng Wei, Huan Zhang in Environmental Science and Pollution Resear… (2015)

  19. No Access

    Article

    Preparation and electrochemical properties of SnO2-Sb-Ni-Ce oxide anode for phenol oxidation

    A novel Ni-Ce co-doped SnO2-Sb anode with macroporous titanium sheet as substrate (mp-Ti/SnO2-Sb-Ni-Ce anode) was prepared by modified sol–gel method. The surface morphology, the crystal structure, and the valenc...

    Zhirong Sun, Huan Zhang, Xuefeng Wei, **aoyue Ma in Journal of Solid State Electrochemistry (2015)

  20. No Access

    Article

    Surgical trauma induces postoperative T-cell dysfunction in lung cancer patients through the programmed death-1 pathway

    The programmed death-1 (PD-1) and programmed death ligand-1 (PD-L1) pathway have been shown to be involved in tumor-induced and sepsis-induced immunosuppression. However, whether this pathway is involved in th...

    **bo Xu, ** Zhang, Zhirong Sun, Yun Wang in Cancer Immunology, Immunotherapy (2015)

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