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  1. Article

    Open Access

    The synergistic inhibitory effect of somatostatin-doxorubicin co-treatment on gallbladder carcinoma

    Gallbladder cancer is the most common billiary tract malignancy and carries a very poor prognosis. Somatostatin was recently shown to play an important role in the development of various tumors. In the current...

    Ji-Yu Li, Zhi-Wei Quan, Qiang Zhang, Jian-Wen Liu in BMC Cancer (2007)

  2. Article

    Open Access

    Relationship between H.Pylori infection and clinicopathological features and prognosis of gastric cancer

    Aimed to assess the relationship between H.Pylori and the clinicopathological features and prognosis of gastric cancer by quantitative detection of H.Pylori.

    Hai-Bo Qiu, Li-Yi Zhang, Rajiv-Prasad Keshari, Guo-Qiang Wang, Zhi-Wei Zhou in BMC Cancer (2010)

  3. Article

    Open Access

    Activated mammalian target of rapamycin is a potential therapeutic target in gastric cancer

    The mammalian target of rapamycin (mTOR) plays a key role in cellular growth and homeostasis. The purpose of our present study is to investigate the expression of activated mTOR (p-mTOR) in gastric cancer pati...

    Da-zhi Xu, Qi-rong Geng, Ying Tian, Mu-yan Cai, **n-juan Fang, You-qing Zhan in BMC Cancer (2010)

  4. Article

    Open Access

    The extramural metastasis might be categorized in lymph node staging for colorectal cancer

    The objective of this study is to assess the clinical significance and prognostic impact of extramural metastasis in colorectal carcinoma and establish an optimal categorization in the staging system.

    Hai-Bo Qiu, Gong Chen, Rajiv P Keshari, Hui-Yan Luo, Wang Fang, Miao-Zhen Qiu in BMC Cancer (2011)

  5. Article

    Open Access

    Higher proliferation of peritumoral endothelial cells to IL-6/sIL-6R than tumoral endothelial cells in hepatocellular carcinoma

    This study aimed to explore the responses to the interleukin-6 (IL-6)/soluble interleukin-6 receptor (sIL-6R) complex in peritumoral endothelial cells (PECs) and tumor endothelial cells (TECs), as well as dete...

    Peng-Yuan Zhuang, Jian-Dong Wang, Zhao-Hui Tang, Xue-** Zhou, Zhi-Wei Quan in BMC Cancer (2015)

  6. Article

    Open Access

    Nemo-like kinase as a negative regulator of nuclear receptor Nurr1 gene transcription in prostate cancer

    Nurr1, a member of the orphan receptor family, plays an important role in several types of cancer. Our previous work demonstrated that increased expression of Nurr1 plays a significant role in the initiation a...

    Jian Wang, Zhi-Hong Yang, Hua Chen, Hua-Hui Li, Li-Yong Chen, Zhu Zhu in BMC Cancer (2016)

  7. Article

    Open Access

    ZBP-89 and Sp1 contribute to Bak expression in hepatocellular carcinoma cells

    Kruppel family member zinc binding protein 89 (ZBP-89), also known as ZNF148, regulates Bak expression via binding to GC-rich promoter domain. It is not clear if other GC-rich binding factors, such as Sp famil...

    **a Kong, Pin Xu, Wei-Jie Cai, Huai-Gao Wang, Bin-Bin Li, Guo-Liang Huang in BMC Cancer (2018)

  8. Article

    Open Access

    Effect of surgical liver resection on circulating tumor cells in patients with hepatocellular carcinoma

    This study explored the effect of liver resection on perioperative circulating tumor cells (CTCs) and found that the prognostic significance of surgery was associated with changes in CTC counts in patients wit...

    **g-**g Yu, Wei **ao, Shui-lin Dong, Hui-fang Liang, Zhi-wei Zhang in BMC Cancer (2018)

  9. Article

    Open Access

    Risk factors of lymph node metastasis or lymphovascular invasion for early gastric cancer: a practical and effective predictive model based on international multicenter data

    Most lymph node metastasis (LNM) models for early gastric cancer (EGC) include lymphovascular invasion (LVI) as a predictor. However, LVI must be confirmed by postoperative pathology. In this study, we aimed t...

    Jian-**an Lin, Zu-Kai Wang, Wei Wang, Jacopo Desiderio, Jian-Wei **e in BMC Cancer (2019)

  10. Article

    Open Access

    Efficacy and safety of self-expanding metallic stent placement followed by neoadjuvant chemotherapy and scheduled surgery for treatment of obstructing left-sided colonic cancer

    This study aimed to evaluate the safety and feasibility of self-expanding metallic stent (SEMS) followed by neoadjuvant chemotherapy prior to elective surgery for obstructing left-sided colon cancer.

    Jia Gang Han, Zhen Jun Wang, Wei Gen Zeng, Yan Bin Wang, Guang Hui Wei in BMC Cancer (2020)

  11. Article

    Open Access

    Palliative Gastrectomy versus Gastrojejunostomy for advanced Gastric cancer with outlet obstruction: a propensity score matching analysis

    Gastric outlet obstruction (GOO) is a late complication of advanced gastric cancer, and it is controversial how to select the therapeutic strategies: gastrojejunostomy and palliative gastrectomy? Therefore, th...

    **ao-Jiang Chen, Guo-Ming Chen, Yi-Cheng Wei, Hong Yu, **-Cheng Wang in BMC Cancer (2021)

  12. Article

    Open Access

    LINC00852 promotes the proliferation and invasion of ovarian cancer cells by competitively binding with miR-140-3p to regulate AGTR1 expression

    Dysregulation of long non-coding RNAs (lncRNAs) has been identified in ovarian cancer. However, the expression and biological functions of LINC00852 in ovarian cancer are not understood.

    Zhi-wei Qiao, Ying Jiang, Ling Wang, Lei Wang, **g Jiang, **g-ru Zhang in BMC Cancer (2021)

  13. Article

    Open Access

    Comparison of response evaluation criteria in solid tumors and tumor regression grade in evaluating the effect of preoperative systemic therapy of gastric cancer

    Both Response Evaluation Criteria in Solid Tumors (RECIST) and tumor regression grade (TRG) play key roles in evaluating tumor response. We analyzed the consistency of TRG and RECIST 1.1 for gastric cancer (GC...

    Ming-Yu Lai, Shi-Yang Kang, Yu-Ting Sun, Ting-Ting Quan, Shi-Xun Lu in BMC Cancer (2022)

  14. Article

    Open Access

    A radiomics signature derived from CT imaging to predict MSI status and immunotherapy outcomes in gastric cancer: a multi-cohort study

    Accurate microsatellite instability (MSI) testing is essential for identifying gastric cancer (GC) patients eligible for immunotherapy. We aimed to develop and validate a CT-based radiomics signature to predic...

    Peng-chao Zhan, Shuo Yang, **ng Liu, Yu-yuan Zhang, Rui Wang, Jia-xing Wang in BMC Cancer (2024)