7 Result(s)
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Article
Zhenming Guo
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Article
A novel heterozygous missense variant of the ARID4A gene identified in Han Chinese families with schizophrenia-diagnosed siblings that interferes with DNA-binding activity
ARID4A plays an important role in regulating gene expression and cell proliferation. ARID4A belongs to the AT-rich interaction domain (ARID)-containing family, and a PWWP domain immediately precedes its ARID regi...
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Open AccessEffect of exercise and diet intervention in NAFLD and NASH via GAB2 methylation
Nonalcoholic fatty liver disease (NAFLD) is a disorder that extends from simple hepatic steatosis to nonalcoholic steatohepatitis (NASH), which is effectively alleviated by lifestyle intervention. Nevertheless...
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Open AccessA study of negative life events driven depressive symptoms and academic engagement in Chinese college students
Negative life events (NLEs) are an important predictor of depressive symptoms (DS). College students experiencing NLEs are at risk of develo** DS that could further weaken their academic engagement (AE), whi...
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Open AccessRole of rs454214 in Personality mediated Depression and Subjective Well-being
Happiness and depression are interlinked and both heritable, while personality, as an important predictor of them, shares the genetic basis with them. We conjecture that genetic factors of depression can affec...
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Metabolomic profiling on rat brain of prenatal malnutrition: implicated for oxidative stress and schizophrenia
Schizophrenia is a kind of neurodevelopmental disease. Epidemiological data associates schizophrenia with prenatal exposure to famine. Relevant prenatal protein deprivation (PPD) rodent models support this res...
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Author Correction: Genetically engineered cerebral organoids model brain tumor formation
In the originally published paper, the “before” image for the afatinib condition in Fig. 6c was incorrect. Instead of an image displaying a GBM-3 neoplastic organoid before afatinib treatment, this panel showe...
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Genetically engineered cerebral organoids model brain tumor formation
Brain tumors are among the most lethal and devastating cancers. Their study is limited by genetic heterogeneity and the incompleteness of available laboratory models. Three-dimensional organoid culture models ...
