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  1. No Access

    Article

    Robotic natural orifice specimen extraction surgery versus robotic transabdominal specimen extraction surgery for early-stage rectal cancer: a multicenter propensity score-matched analysis (in China)

    Despite the global increase in the adoption of robotic natural orifice specimen extraction surgery (R-NOSES), its advantages over robotic transabdominal specimen extraction surgery (R-TSES) for treating early-...

    Dongning Liu, Guodong He, Hongliang Yao, Xu Guan, Guiyu Wang in Surgical Endoscopy (2024)

  2. Article

    Open Access

    HERC3 regulates epithelial-mesenchymal transition by directly ubiquitination degradation EIF5A2 and inhibits metastasis of colorectal cancer

    E3 ligase is widely reported to exert fundamental functions in cancers. Through rigorous bioinformatic analysis concentrating E3 ligases based on data from Genotype-Tissue Expression (GTEx) and data from The C...

    Zhiyuan Zhang, Guodong He, Yang Lv, Yu Liu, Zhengchuan Niu in Cell Death & Disease (2022)

  3. Article

    Open Access

    Norcantharidin Suppresses Colon Cancer Cell Epithelial-Mesenchymal Transition by Inhibiting the αvβ6-ERK-Ets1 Signaling Pathway

    Norcantharidin (NCTD) is an efficacious anti-cancer drug that has been used in China for many years, but its underlying mechanism of action is still not fully understood. In the present study, we found that NC...

    Cheng Peng, Zequn Li, Zhengchuan Niu, Wei Niu, Zongquan Xu in Scientific Reports (2016)

  4. No Access

    Article

    Epieriocalyxin A Induces Cell Apoptosis Through JNK and ERK1/2 Signaling Pathways in Colon Cancer Cells

    Colorectal cancer is one of the most commonly diagnosed cancers in the world. Currently, drug resistance of cancer cell to chemotherapy is a major cause for cancer recurrence and death of the patients; therefo...

    Zhou Wang, Zhijie Xu, Zhengchuan Niu, Benjia Liang in Cell Biochemistry and Biophysics (2015)

  5. Article

    Open Access

    Integrin αvβ6 and transcriptional factor Ets-1 act as prognostic indicators in colorectal cancer

    Both transcriptional factor Ets-1 and integrin αvβ6 play an important role in the development and progression of cancer. The aim of our study was to investigate the expression of Integrin αvβ6 and Ets-1, two p...

    Cheng Peng, Huijie Gao, Zhengchuan Niu, Ben Wang, Zhen Tan, Weibo Niu in Cell & Bioscience (2014)

  6. Article

    Open Access

    Protein expression of eIF4E and integrin αvβ6 in colon cancer can predict clinical significance, reveal their correlation and imply possible mechanism of interaction

    Both eukaryotic translation initiation factor 4E (eIF4E) and integrin αvβ6 play an important role in the development and progression of cancer. The aim of this study was to investigate the expression of eIF4E ...

    Zhengchuan Niu, Jiayong Wang, Shahbaz Muhammad, Weibo Niu, Enyu Liu in Cell & Bioscience (2014)