14 Result(s)

Article

Clinical Significance of PAC-1, CD62P, and Platelet-Leukocyte Aggregates in Acute Ischemic Stroke

We studied diagnostic and treatment values of the blood levels of platelet activation markers PNA, PMA, PLyA, PAC-1, and CD62P in 30 patients with acute ischemic stroke (median NIHSS score 4 (2; 6)) before and...

Y. Zhang, Z. Ma, Q. Liu, Q. Qiao, Q. Wu… in Bulletin of Experimental Biology and Medic… (2022)

Article

Loss of KLF4 and consequential downregulation of Smad7 exacerbate oncogenic TGF-β signaling in and promote progression of hepatocellular carcinoma

Hyperactivation of transforming growth factor-β (TGF-β) signaling pathway is a common feature of hepatocellular carcinoma (HCC) progression. However, the driver factors leading to enhanced TGF-β activity are n...

H Sun, Z Peng, H Tang, D **e, Z Jia, L Zhong, S Zhao, Z Ma, Y Gao, L Zeng… in Oncogene (2017)

Article

RNF126 promotes homologous recombination via regulation of E2F1-mediated BRCA1 expression

RNF126 is an E3 ubiquitin ligase. The deletion of RNF126 gene was observed in a wide range of human cancers and is correlated with improved disease-free and overall survival. These data highlight the clinical rel...

Y Wang, O Deng, Z Feng, Z Du, X **ong, J Lai, X Yang, M Xu, H Wang, D Taylor… in Oncogene (2016)

Article

MALT1 is required for EGFR-induced NF-κB activation and contributes to EGFR-driven lung cancer progression

The transcription factor nuclear factor kappa B (NF-κB) has been implicated in having a crucial role in the tumorigenesis of many types of human cancers. Although epidermal growth factor receptor (EGFR) can di...

D Pan, C Jiang, Z Ma, M Blonska, M J You, X Lin in Oncogene (2016)

Article

p66^Shc restrains Ras hyperactivation and suppresses metastatic behavior

Normal tissue cells survive and proliferate only while anchored to solid substrate. Conversely, transformed cells both survive and proliferate following detachment, having lost attachment context through uncle...

Z Ma, Z Liu, R-F Wu, L S Terada in Oncogene (2010)

Article

Mortalin controls centrosome duplication via modulating centrosomal localization of p53

Abnormal amplification of centrosomes, commonly found in human cancer, is the major cause of mitotic defects and chromosome instability in cancer cells. Like DNA, centrosomes duplicate once in each cell cycle,...

Z Ma, H Izumi, M Kanai, Y Kabuyama, N G Ahn, K Fukasawa in Oncogene (2006)

Article

Increased susceptibility to apoptosis in CD45⁺ myeloma cells accompanied by the increased expression of VDAC1

Expression of CD45 is quite variable in human myeloma cells and cell lines, such as U266, and CD45⁺ U266 proliferates in response to a growth factor, interleukin-6. Here, we show that CD45⁺ myeloma cell lines wer...

S Liu, H Ishikawa, N Tsuyama, F-J Li, S Abroun, K-i Otsuyama, X Zheng, Z Ma… in Oncogene (2006)

Article

Prolonged gene expression in mouse lung endothelial cells following transfection with Epstein–Barr virus-based episomal plasmid

The development of a strategy to deliver a gene to pulmonary endothelium will be useful for gene function study and for pulmonary gene therapy. Cationic lipidic vectors are efficient in gene transfer to pulmon...

J Zhang, A Wilson, S Alber, Z Ma, Z-L Tang, E Satoh, O Mazda, S Watkins… in Gene Therapy (2003)

Article

Redirecting adenovirus to pulmonary endothelium by cationic liposomes

Somatic gene transfer to the pulmonary endothelium may be a useful strategy for modifying the phenotype of endothelium and/or vascular smooth muscle in disorders such as primary pulmonary hypertension, ARDS or...

Z Ma, Z Mi, A Wilson, S Alber, PD Robbins, S Watkins, B Pitt, S Li in Gene Therapy (2002)

Article

Cloning and sequencing of dog cDNA encoding the T-cell costimulatory molecule (CTLA-4)

T. S. Khatlani, K. Ohno, Z. Ma, H. Inokuma, T. Onishi in Immunogenetics (2000)