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  1. Article

    Open Access

    Bilirubin neurotoxicity is associated with proteasome inhibition

    The molecular mechanism underlying bilirubin neurotoxicity remains obscure. Ubiquitin–proteasome system-mediated proteolysis is pivotal to virtually all cellular processes and cell survival. Here we report for...

    Hongbiao Huang, Mingxing Guo, Ningning Liu, Chong Zhao, Haoyu Chen in Cell Death & Disease (2017)

  2. Article

    Open Access

    Microbiota transplantation: concept, methodology and strategy for its modernization

    Fecal microbiota transplantation (FMT) has become a research focus of biomedicine and clinical medicine in recent years. The clinical response from FMT for different diseases provided evidence for microbiota-h...

    Faming Zhang, Bota Cui, **ngxiang He, Yuqiang Nie, Kaichun Wu in Protein & Cell (2018)

  3. Article

    Open Access

    F. prausnitzii and its supernatant increase SCFAs-producing bacteria to restore gut dysbiosis in TNBS-induced colitis

    An increasing number of studies have shown that Faecalibacterium prausnitzii (F. prausnitzii) is a promising anti-inflammatory bacterium that colonizes in the gut and that gut microbiota dysbiosis plays an import...

    Youlian Zhou, Haoming Xu, **g Xu, Xue Guo, Hailan Zhao, Ye Chen in AMB Express (2021)

  4. Article

    Open Access

    Pretreatment with an antibiotics cocktail enhances the protective effect of probiotics by regulating SCFA metabolism and Th1/Th2/Th17 cell immune responses

    Probiotics are a potentially effective therapy for inflammatory bowel disease (IBD); IBD is linked to impaired gut microbiota and intestinal immunity. However, the utilization of an antibiotic cocktail (Abx) p...

    **g Xu, Haoming Xu, Xue Guo, Hailan Zhao, Jiaqi Wang, Jianhong Li in BMC Microbiology (2024)