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  1. Article

    Open Access

    Pretreatment with an antibiotics cocktail enhances the protective effect of probiotics by regulating SCFA metabolism and Th1/Th2/Th17 cell immune responses

    Probiotics are a potentially effective therapy for inflammatory bowel disease (IBD); IBD is linked to impaired gut microbiota and intestinal immunity. However, the utilization of an antibiotic cocktail (Abx) p...

    **g Xu, Haoming Xu, Xue Guo, Hailan Zhao, Jiaqi Wang, Jianhong Li in BMC Microbiology (2024)

  2. Article

    Open Access

    F. prausnitzii and its supernatant increase SCFAs-producing bacteria to restore gut dysbiosis in TNBS-induced colitis

    An increasing number of studies have shown that Faecalibacterium prausnitzii (F. prausnitzii) is a promising anti-inflammatory bacterium that colonizes in the gut and that gut microbiota dysbiosis plays an import...

    Youlian Zhou, Haoming Xu, **g Xu, Xue Guo, Hailan Zhao, Ye Chen in AMB Express (2021)

  3. Article

    Open Access

    Microbiota transplantation: concept, methodology and strategy for its modernization

    Fecal microbiota transplantation (FMT) has become a research focus of biomedicine and clinical medicine in recent years. The clinical response from FMT for different diseases provided evidence for microbiota-h...

    Faming Zhang, Bota Cui, **ngxiang He, Yuqiang Nie, Kaichun Wu in Protein & Cell (2018)

  4. Article

    Open Access

    Bilirubin neurotoxicity is associated with proteasome inhibition

    The molecular mechanism underlying bilirubin neurotoxicity remains obscure. Ubiquitin–proteasome system-mediated proteolysis is pivotal to virtually all cellular processes and cell survival. Here we report for...

    Hongbiao Huang, Mingxing Guo, Ningning Liu, Chong Zhao, Haoyu Chen in Cell Death & Disease (2017)