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Article
Open AccessSalinity-responsive histone PTMs identified in the gills and gonads of Mozambique tilapia (Oreochromis mossambicus)
Histone post-translational modifications (PTMs) are epigenetic marks that can be induced by environmental stress and elicit heritable patterns of gene expression. To investigate this process in an ecological c...
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Article
Open AccessConstruction and in vitro evaluation of pH-sensitive nanoparticles to reverse drug resistance of breast cancer stem cells
Breast cancer is a major threat to safety and health of women. The breast cancer stem cells (BCSCs) have multi-drug resistance to chemotherapy drugs, which leads to chemotherapy failure. We proposed a strategy...
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Article
Combining Low-Dose Rituximab and Bortezomib as Immunosuppressive Therapy for Acquired Hemophilia A: 6 Case Series
Acquired hemophilia A (AHA) is a rare bleeding disorder caused by autoantibodies against factor VIII. Persistently positive inhibitor titers increase the risk of bleeding. Upfront combined regimen with multipl...
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Article
Open AccessGlucose oxidase and metal catalysts combined tumor synergistic therapy: mechanism, advance and nanodelivery system
Cancer has always posed a significant threat to human health, prompting extensive research into new treatment strategies due to the limitations of traditional therapies. Starvation therapy (ST) has garnered co...
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Article
Open AccessThe mutation rate of rpoB gene showed an upward trend with the increase of MIRU10, MIRU39 and QUB4156 repetitive number
Mycobacterial interspersed repetitive unit-variable number tandem repeat (MIRU-VNTR) is a frequently used ty** method for identifying the Bei**g genotype of Mycobacterium tuberculosis (Mtb), which is easily tr...
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Article
Open AccessAge and sex trend differences in hemoglobin levels in China: a cross-sectional study
Both age and gender are the influence factors of hemoglobin concentration. However, the changing trend of hemoglobin levels between males and females with age remains unclear. This study aimed to explore their...
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Article
Open AccessPrediction of carotid plaque by blood biochemical indices and related factors based on Fisher discriminant analysis
This study aims to establish the predictive model of carotid plaque formation and carotid plaque location by retrospectively analyzing the clinical data of subjects with carotid plaque formation and normal peo...
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Article
Open AccessMechanisms of bone pain: Progress in research from bench to bedside
The field of research on pain originating from various bone diseases is expanding rapidly, with new mechanisms and targets asserting both peripheral and central sites of action. The scope of research is broade...
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Article
Open AccessImplications of gender-based variabilities in bone mineral density and hemoglobin levels
Studies reported that there is a relationship between volumetric bone mineral density (vBMD) and hemoglobin (HGB) in sickle cell anemia, chronic obstructive pulmonary disease, inflammatory bowel disease, and c...
